Non-Metastatic Cells 2 Recombinant Protein | NME2 recombinant protein
Recombinant Rat Non-Metastatic Cells 2
Sterile Filtered clear solution.
Description: NME2 Rat Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 175 amino acids (1-152 a.a) and having a molecular mass of 19.7kDa. NME2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
NCBI and Uniprot Product Information
Uniprot Description
NME2: Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity. Belongs to the NDK family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.13.3; EC 2.7.4.6; Kinase, nucleoside diphosphate; Kinase, other; NDK family; Nuclear receptor co-regulator; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Other group
Cellular Component: cytoplasm; focal adhesion; intermediate filament; lamellipodium; mitochondrial membrane; mitochondrion; myelin sheath; nucleus; perinuclear region of cytoplasm; ruffle
Molecular Function: drug binding; enzyme binding; fatty acid binding; intermediate filament binding; nucleoside diphosphate kinase activity; protein serine/threonine kinase activity
Biological Process: CTP biosynthetic process; GTP biosynthetic process; integrin-mediated signaling pathway; negative regulation of apoptosis; negative regulation of myeloid leukocyte differentiation; nucleoside diphosphate phosphorylation; nucleoside triphosphate biosynthetic process; positive regulation of cAMP biosynthetic process; positive regulation of epithelial cell proliferation; positive regulation of keratinocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; protein amino acid autophosphorylation; protein oligomerization; regulation of apoptosis; regulation of epidermis development; UTP biosynthetic process
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Product Notes
The NME2 nme2 (Catalog #AAA140671) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHHSSGLVPR GSH MGSMAN LERTFIAIKP DGVQ RGLVGEIIKR FEQKGFRLVA MKFLRASEEH LKQHYIDLKD RPFFPGLVKY MNSGPVVAMV WEGLNVVKTG RVMLGETNPA DSKPGTIRGD FCIQVGRNII HGSDSVESAE KEIGLWFKPE ELIDYKSCAH DWVYE. It is sometimes possible for the material contained within the vial of "Non-Metastatic Cells 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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