Dog non-metastatic cells 1, protein (NM23A) expressed in ELISA Kit | NME1 elisa kit
Dog Nucleoside diphosphate kinase A, NME1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair UniRule annotationHAMAP-Rule:MF_00451
Catalytic activity: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.UniRule annotationHAMAP-Rule:MF_00451
Cofactor: Magnesium UniRule annotationHAMAP-Rule:MF_00451
Enzyme regulation: Autophosphorylation at His-118 increases serine/threonine protein kinase activity of the enzyme. Interaction with the SET complex inhibits exonuclease activity UniRule annotationHAMAP-Rule:MF_00451
Similar Products
Product Notes
The Dog NME1 nme1 (Catalog #AAA9325983) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9325983 ELISA Kit recognizes Dog NME1. It is sometimes possible for the material contained within the vial of "non-metastatic cells 1, protein (NM23A) expressed in, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
