Nance-Horan syndrome protein (NHS) Recombinant Protein | NHS recombinant protein

Recombinant Human Nance-Horan syndrome protein (NHS) , partial

• Gene Names: NHS; CXN; SCML1; CTRCT40
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Nance-Horan syndrome protein (NHS); Recombinant Human Nance-Horan syndrome protein (NHS); partial; NHS recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1,473

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for NHS recombinant protein

This gene encodes a protein containing four conserved nuclear localization signals. The encoded protein may function during the development of the eyes, teeth, and brain. Mutations in this gene have been shown to cause Nance-Horan syndrome. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 209862849
• NCBI GeneID: 4810
• NCBI Accession #: NP_001129496.1
• NCBI GenBank Nucleotide #: NM_001136024.3
• UniProt Accession #: Q6T4R5; Q5J7Q0; Q5J7Q1; Q68DR5; B7ZVX8; E2DH69
• Molecular Weight: 160,753 Da
• NCBI Official Full Name: Nance-Horan syndrome protein isoform 2
• NCBI Official Synonym Full Names: NHS actin remodeling regulator
• NCBI Official Symbol: NHS
• NCBI Official Synonym Symbols: CXN; SCML1; CTRCT40
• NCBI Protein Information: Nance-Horan syndrome protein
• UniProt Protein Name: Nance-Horan syndrome protein
• Protein Family: Nance-Horan syndrome protein
• UniProt Gene Name: NHS

NCBI Description

This gene encodes a protein containing four conserved nuclear localization signals. The encoded protein functions in eye, tooth, craniofacial and brain development, and it can regulate actin remodeling and cell morphology. Mutations in this gene have been shown to cause Nance-Horan syndrome, and also X-linked cataract-40. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2014]

Uniprot Description

May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development.