Human NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) ELISA Kit | NHP2L1 elisa kit

Human NHP2-like protein 1, NHP2L1 ELISA Kit

Cat. Num. AAA9321623

• Gene Names: NHP2L1; FA1; FA-1; NHPX; 15.5K; OTK27; SNU13; SSFA1; SPAG12; SNRNP15-5
• Reactivity: Human
• Synonyms: NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae); Human NHP2-like protein 1; NHP2L1 ELISA Kit; Human NHP2-like protein 1 (NHP2L1) ELISA kit; CTA-216E10.8; 15.5K; FA-1; FA1; NHPX; OTK27; SNRNP15-5; SNU13; SPAG12; SSFA1; NHP2 non-histone chromosome protein 2-like 1; OTTHUMP00000199329; [U4/U6.U5] tri-snRNP 15.5 kD RNA binding protein; high mo; NHP2L1 elisa kit

• Reactivity: Human

• Assay Type: Quantitative Sandwich
• Detection Range: 3.12ng/ml-100ng/ml
• Sensitivity: 1.0ng/ml
• Intra-assay Precision: Intra-assay CV (%)is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for NHP2L1 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of NHP2L1 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 51317376
• NCBI GeneID: 4809
• NCBI Accession #: NP_001003796.1
• NCBI GenBank Nucleotide #: NM_001003796.1
• UniProt Accession #: P55769
• Molecular Weight: 14,174 Da
• NCBI Official Full Name: NHP2-like protein 1
• NCBI Official Synonym Full Names: NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
• NCBI Official Symbol: NHP2L1
• NCBI Official Synonym Symbols: FA1; FA-1; NHPX; 15.5K; OTK27; SNU13; SSFA1; SPAG12; SNRNP15-5
• NCBI Protein Information: NHP2-like protein 1; sperm specific antigen 1; U4/U6.U5 tri-snRNP 15.5 kDa protein; non-histone chromosome protein 2-like 1; [U4/U6.U5] tri-snRNP 15.5 kD RNA binding protein; small nuclear ribonucleoprotein 15.5kDa (U4/U6.U5); high mobility group-like nuclear protein 2 homolog 1
• UniProt Protein Name: NHP2-like protein 1
• UniProt Gene Name: NHP2L1
• UniProt Synonym Gene Names: hSNU13
• UniProt Entry Name: NH2L1_HUMAN

NCBI Description

Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

NHP2L1: Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. Belongs to the ribosomal protein L7Ae family.

Protein type: RNA-binding; Nucleolus; RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 22q13

Cellular Component: nucleoplasm; spliceosome; protein complex; nucleolus; nucleus

Molecular Function: snoRNA binding; protein binding; RNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; ribosome biogenesis and assembly; gene expression