Mouse nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein ELISA Kit | NFATC2IP elisa kit
Mouse NFATC2-interacting protein, NFATC2IP ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
NFATC2IP: In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'- methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription, coactivator/corepressor
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding
Biological Process: cytokine production; positive regulation of transcription from RNA polymerase II promoter
Research Articles on NFATC2IP
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Product Notes
The Mouse NFATC2IP nfatc2ip (Catalog #AAA9330741) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9330741 ELISA Kit recognizes Mouse NFATC2IP. It is sometimes possible for the material contained within the vial of "nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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