Neuron Specific Enolase Recombinant Protein
Neuron Specific Enolase, Recombinant, Human (NSE, Gamma-enolase, 2-phospho-D-glycerate hydro-lyase, Neural Enolase, Enolase 2, ENO2)
Applications
Gel Super Shift Assay
Purity
Highly Purified~95% (SDS-PAGE)
Synonyms
Neuron Specific Enolase; Recombinant; Human (NSE; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; Neural Enolase; Enolase 2; ENO2); Neuron Specific Enolase recombinant protein
Purity/Purification
Highly Purified
~95% (SDS-PAGE)
~95% (SDS-PAGE)
Form/Format
Supplied as a liquid in PBS, 50% glycerol.
Applicable Applications for Neuron Specific Enolase recombinant protein
Gel Shift Assay (GS/EMSA)
Application Notes
Suitable for use in ELISA, Western Blot, Dot Blot, Immunohistochemistry and Rapid tests.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Neuron Specific Enolase recombinant protein
The glycolytic enzyme enolase (2-phospho-Dglycerate hydrolyase) exists as several dimeric isoenzymes (aa, ab, ag, bb and gg) composed of three distinct subunits: a, b, and g (alpha, beta, and gamma). Three isoenzymes are found in human brain: aa, ag, and gg. The ag and gg-enoloase isoenzymes are also known as neuron- specific enolase (NSE) as these isoenzymes initially were detected in neurons and neuronendocrine cells. Lung cancer is one of the most spread cancer forms with incidences about 50-100 per 100,000 population. Approximately 20% of the lung cancer is small cell lung cancer. NSE has been shown to be a valuable tumor marker of neuroendocrine origin, particulary in small cell lung cancer and in neuroblastoma. Patients with small cell lung cancer show various proportions of ag and gg isoenzymes. The determination of NSE should detect ag and gg isoforms with the same sensitivity. The antibodies for this particular assay are specific for the g-subunit without cross reactivity with a or b subunits. NSE is reported to be useful marker for lung cancer, neuroblastoma, melnoma, seminoma and in injury of central nervous system. In addition to the above, NSE can be a valuable tool in following-up the effect of chemotherapy of small cell lung cancer, in prognostic evaluation of patients with small cell lung cancer, and in differential identification between cell lung cancer and non-small cell lung cancer.
Product Categories/Family for Neuron Specific Enolase recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
neuron-specific enolase
Similar Products
Product Notes
The Neuron Specific Enolase (Catalog #AAA636131) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Neuron Specific Enolase can be used in a range of immunoassay formats including, but not limited to, Gel Shift Assay (GS/EMSA). Suitable for use in ELISA, Western Blot, Dot Blot, Immunohistochemistry and Rapid tests. Researchers should empirically determine the suitability of the Neuron Specific Enolase for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neuron Specific Enolase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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