Netrin G1/NTNG1 Recombinant Protein | NTNG1 recombinant protein

Netrin G1/NTNG1 Protein, Human, Recombinant (His Tag)

Cat. Num. AAA8121150

• Gene Names: NTNG1; Lmnt1
• Purity: >95% as determined by SDS-PAGE
• Synonyms: Netrin G1/NTNG1; Netrin G1/NTNG1 Protein; Human; Recombinant (His Tag); Human NTNG1/Netrin-G1 Protein (His Tag); Lmnt1 Protein; netrin G1; NTNG1 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >95% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Gly408

• Species: Human
• Endotoxin: <1.0EU per ug protein as determined by the LAL method.
• Predicted N Terminal: Val 19
• Tag: C-His
• Protein Construction: A DNA sequence encoding the human NTNG1 (NP_055732.2)(Met1-Gly408) was expressed with a polyhistidine tag at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for NTNG1 recombinant protein

Background: NTNG1 (Netrin G1) is a Protein Coding gene. This gene encodes a preproprotein that is processed into a secreted protein containing eukaryotic growth factor (EGF)-like domains. NTNG1 is broadly expressed in the brain, kidney, and other tissues. Netrins including NTNG1 are known to be axon guidance factors in the developing brain. It is involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular, and synaptic levels. The NTNG1 protein has an important role in the developing central nervous system, particularly in axonal guidance, signaling, and NMDA receptor function, and was a good candidate gene for Rett syndrome (RTT). They could be very important contributors to the genetic risk for psychosis.

NCBI and Uniprot Product Information

• NCBI GI #: 54312078
• NCBI GeneID: 22854
• NCBI Accession #: NP_055732.2
• NCBI GenBank Nucleotide #: NM_014917.3
• Molecular Weight: 55,660 Da
• NCBI Official Full Name: netrin-G1 isoform G1c
• NCBI Official Synonym Full Names: netrin G1
• NCBI Official Symbol: NTNG1
• NCBI Official Synonym Symbols: Lmnt1
• NCBI Protein Information: netrin-G1
• Protein Family: Netrin

NCBI Description

This gene encodes a preproprotein that is processed into a secreted protein containing eukaroytic growth factor (EGF)-like domains. This protein acts to guide axon growth during neuronal development. Polymorphisms in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2015]