Neuropilin and tolloid-like protein 1 (NETO1) Recombinant Protein | NETO1 recombinant protein

Recombinant Human Neuropilin and tolloid-like protein 1 (NETO1), partial

Cat. Num. AAA1355821

• Gene Names: NETO1; BCTL1; BTCL1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Neuropilin and tolloid-like protein 1 (NETO1); Recombinant Human Neuropilin and tolloid-like protein 1 (NETO1); partial; NETO1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 23-344
• Sequence: TKKGTEKQ TTSETQKSVQ CGTWTKHAEG GIFTSPNYPS KYPPDRECIY IIEAAPRQCI ELYFDEKYSI EPSWECKFDH IEVRDGPFGF SPIIGRFCGQ QNPPVIKSSG RFLWIKFFAD GELESMGFSA RYNFTPDPDF KDLGALKPLP ACEFEMGGSE GIVESIQIMK EGKATASEAV DCKWYIRAPP RSKIYLRFLD YEMQNSNECK RNFVAVYDGS SSVEDLKAKF CSTVANDVML RTGLGVIRMW ADEGSRNSRF QMLFTSFQEP PCEGNTFFCH SNMCINNTLV CNGLQNCVYP WDENHCKEKR KTSLLDQLTN TSGT
• Sequence Length: 322

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for NETO1 recombinant protein

This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. It also has an intracellular FXNPXY-like motif, which has been shown in other proteins to be essential for the internalization of clathrin coated pits during endocytosis. Alternatively spliced transcript variants encoding distinct proteins have been described.

NCBI and Uniprot Product Information

• NCBI GI #: 319918840
• NCBI GeneID: 81832
• NCBI Accession #: NP_001188394.1
• NCBI GenBank Nucleotide #: NM_001201465.2
• UniProt Accession #: Q8TDF5; Q86W85; Q8ND78; Q8TDF4
• Molecular Weight: 60,060 Da
• NCBI Official Full Name: neuropilin and tolloid-like protein 1 isoform 3
• NCBI Official Synonym Full Names: neuropilin and tolloid like 1
• NCBI Official Symbol: NETO1
• NCBI Official Synonym Symbols: BCTL1; BTCL1
• NCBI Protein Information: neuropilin and tolloid-like protein 1
• UniProt Protein Name: Neuropilin and tolloid-like protein 1
• Protein Family: Neuropilin and tolloid-like protein
• UniProt Gene Name: NETO1
• UniProt Synonym Gene Names: BTCL1

NCBI Description

This gene encodes a transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. This protein is thought to play a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2017]

Uniprot Description

Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory ().