Human Nedd4 family interacting protein 2 ELISA Kit | NDFIP2 elisa kit
Human NEDD4 family-interacting protein 2, NDFIP2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
NDFIP2: Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. May modulate EGFR signaling.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 13q31.1
Cellular Component: Golgi membrane; Golgi apparatus; intracellular membrane-bound organelle; mitochondrion; perinuclear region of cytoplasm; endoplasmic reticulum; cytoplasm; integral to membrane
Molecular Function: protein binding; signal transducer activity; WW domain binding
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of protein ubiquitination; negative regulation of protein transport; signal transduction; negative regulation of transporter activity
Research Articles on NDFIP2
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Product Notes
The Human NDFIP2 ndfip2 (Catalog #AAA9338693) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9338693 ELISA Kit recognizes Human NDFIP2. It is sometimes possible for the material contained within the vial of "Nedd4 family interacting protein 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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