Neurocalcin Delta (NCALd) Recombinant Protein | NCALd recombinant protein

Recombinant Neurocalcin Delta (NCALd)

Cat. Num. AAA2086929

• Applications: SDS-Page, Western Blot
• Purity: > 90%
• Synonyms: Neurocalcin Delta (NCALd); Recombinant Neurocalcin Delta (NCALd); NCALd recombinant protein

• Host: E Coli
• Purity/Purification: > 90%
• Form/Format: Freeze-dried powder
• Sequence Length: 193

• Applicable Applications for NCALd recombinant protein: Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
• Fragment: Gly2~Phe193
• Tag: N-terminal His-tag
• Buffer Formulation: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Source Note: Prokaryotic expression
• Organism Species: Human
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Isoelectric Point: 5.2
• Usage: Reconstitute in sterile ddH2O.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

Product Categories/Family for NCALd recombinant protein

Recombinant Protein

NCBI and Uniprot Product Information

• NCBI GI #: 98985783
• NCBI GeneID: 83988
• NCBI Accession #: NP_001035714.1
• NCBI GenBank Nucleotide #: NM_001040624.1
• UniProt Accession #: P61601; P29554; Q8IYC3; Q9H0W2
• Molecular Weight: 25.8kDa
• NCBI Official Full Name: neurocalcin-delta
• NCBI Official Synonym Full Names: neurocalcin delta
• NCBI Official Symbol: NCALD
• NCBI Protein Information: neurocalcin-delta
• UniProt Protein Name: Neurocalcin-delta
• Protein Family: Neurocalcin
• UniProt Gene Name: NCALD

NCBI Description

This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

NCALD: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions. Belongs to the recoverin family.

Chromosomal Location of Human Ortholog: 8q22.3

Cellular Component: cytosol; intracellular

Molecular Function: actin binding; clathrin binding; ligand-gated ion channel activity; protein binding; tubulin binding