NAPG recombinant protein

NAPG Protein, Human, Recombinant (His Tag)

Cat. Num. AAA8121770

• Gene Names: NAPG; GAMMASNAP
• Purity: >85% as determined by SDS-PAGE
• Synonyms: NAPG; NAPG Protein; Human; Recombinant (His Tag); Human NAPG/Gamma SNAP Protein (His Tag); GAMMASNAP Protein; N-ethylmaleimide-sensitive factor attachment protein; gamma; NAPG recombinant protein

• Host: E Coli
• Purity/Purification: >85% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile 50mM Tris, 100mM NaCl, 10% Glycerol, 1mM DTT, pH8.0. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Cys312

• Species: Human
• Predicted N Terminal: His
• Tag: N-His
• Protein Construction: A DNA sequence encoding the human NAPG (AAH01889.1)(Met1-Cys312) was expressed with a polyhistidine tag at the N-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for NAPG recombinant protein

Background: NAPG (NSF Attachment Protein Gamma, also known as gamma SNAP) is a Protein Coding gene. This gene encodes soluble NSF attachment protein gamma. The encoded protein mediates platelet exocytosis and controls the membrane fusion events of this process. NAPG is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. NAPG belongs to the SNAP family. It is widely expressed in the brain, thyroid, and other tissues. SNAPs enable N-ethyl-maleimide-sensitive fusion protein (NSF) to bind to target membranes. NSF and SNAPs appear to be general components of the intracellular membrane fusion apparatus, and their action at specific sites of fusion must be controlled by SNAP receptors particular to the membranes being fused.

References

Lemons PP. et al., 1997, J Cell Biol. 117 (3): 531-8. Chen D. et al., 2001, J Biol Chem. 276 (16): 13127-35. Whiteheart SW. et al., 1992, J Biol Chem. 267 (17): 12239-43.

NCBI and Uniprot Product Information

• NCBI GI #: 12804881
• NCBI GeneID: 8774
• Molecular Weight: 25,662 Da
• NCBI Official Full Name: N-ethylmaleimide-sensitive factor attachment protein, gamma
• NCBI Official Synonym Full Names: N-ethylmaleimide-sensitive factor attachment protein, gamma
• NCBI Official Symbol: NAPG
• NCBI Official Synonym Symbols: GAMMASNAP
• NCBI Protein Information: gamma-soluble NSF attachment protein; SNAP-gamma; gamma SNAP
• Protein Family: Ferredoxin-type protein

NCBI Description

This gene encodes soluble NSF attachment protein gamma. The soluble NSF attachment proteins (SNAPs) enable N-ethyl-maleimide-sensitive fusion protein (NSF) to bind to target membranes. NSF and SNAPs appear to be general components of the intracellular membrane fusion apparatus, and their action at specific sites of fusion must be controlled by SNAP receptors particular to the membranes being fused. The product of this gene mediates platelet exocytosis and controls the membrane fusion events of this process.[provided by RefSeq, Dec 2008]