N-6 Adenine-Specific DNA Methyltransferase 1 Recombinant Protein | N6AMT1 recombinant protein
Recombinant Human N-6 Adenine-Specific DNA Methyltransferase 1
Gene Names
N6AMT1; MTQ2; HEMK2; N6AMT; PRED28; C21orf127; m.HsaHemK2P
Purity
Greater than 85% as determined by SDS-PAGE.
Synonyms
N-6 Adenine-Specific DNA Methyltransferase 1; Recombinant Human N-6 Adenine-Specific DNA Methyltransferase 1; N6AMT1 Human; N-6 Adenine-Specific DNA Methyltransferase 1 Human Recombinant; N-6 Adenine-Specific DNA Methyltransferase 1 (Putative); N(6)-Adenine-Specific DNA Methyltransferase 1; HemK Methyltransferase Family Member 2; M.HsaHemK2P; C21orf127; HEMK2; Chromosome 21 Open Reading Frame 127; N6-DNA-Methyltransferase; EC 2.1.1.-; PRED28; N6AMT; MTQ2; HemK methyltransferase family member 2; N6AMT1 recombinant protein
Host
E Coli
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Form/Format
N6AMT1 protein solution (0.25 mg/ml) containing Phosphate buffered saline (pH7.4), 20% glycerol and 1mM DTT.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAGENFA TPFHGHVGRG AFSDVYEPAE DTFLLLNALE AAAAELAGVEICLEVGSGSG VVSAFLASMI GPQALYMCTD INPEAAACTL ETARCNKVHI QPVITDLVKG LLPRLTEKVDLLVFNPPYVV TPPQEVGSHG IEAAWAGGRN GREVMDRFFPLVPDLLSPRG LFYLVTIKEN NPEEILKIMK TKGLQGTTAL SRQAGQETLSVLKFTKS
Sequence Length
214
Related Product Information for N6AMT1 recombinant protein
Introduction: N-6 Adenine-Specific DNA Methyltransferase 1, also known as N6AMT1 is part of the methyltransferase family. N6AMT1 is implicated in the methylation of release factor I during translation termination. In addition, N6AMT1 is involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid.
Description: N6AMT1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 237 amino acids (1-214 a.a) and having a molecular mass of 25.3kDa. N6AMT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Description: N6AMT1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 237 amino acids (1-214 a.a) and having a molecular mass of 25.3kDa. N6AMT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for N6AMT1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,756 Da
NCBI Official Full Name
hemK methyltransferase family member 2 isoform 1
NCBI Official Synonym Full Names
N-6 adenine-specific DNA methyltransferase 1 (putative)
NCBI Official Symbol
N6AMT1
NCBI Official Synonym Symbols
MTQ2; HEMK2; N6AMT; PRED28; C21orf127; m.HsaHemK2P
NCBI Protein Information
hemK methyltransferase family member 2
UniProt Protein Name
HemK methyltransferase family member 2
Protein Family
UniProt Gene Name
N6AMT1
UniProt Synonym Gene Names
C21orf127; HEMK2
UniProt Entry Name
HEMK2_HUMAN
Uniprot Description
N6AMT1: Heterodimeric methyltransferase that catalyzes N5- methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid. Belongs to the eukaryotic/archaeal PrmC-related family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.1.1.-; Methyltransferase
Chromosomal Location of Human Ortholog: 21q21.3
Cellular Component: cytoplasm; cytosol; protein complex
Molecular Function: protein binding; protein methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity
Biological Process: methylation; positive regulation of cell growth; translational termination
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Product Notes
The N6AMT1 n6amt1 (Catalog #AAA140989) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMAG ENFA TPFHGHVGRG AFSDVYEPAE DTFLLLNALE AAAAELAGVE ICLEVGSGSG VVSAFLASMI GPQALYMCTD INPEAAACTL ETARCNKVHI QPVITDLVKG LLPRLTEKVD LLVFNPPYVV TPPQEVGSHG IEAAWAGGRN GREVMDRFFP LVPDLLSPRG LFYLVTIKEN NPEEILKIMK TKGLQGTTAL SRQAGQETLS VLKFTKS. It is sometimes possible for the material contained within the vial of "N-6 Adenine-Specific DNA Methyltransferase 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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