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Human Probable histone acetyltransferase ELISA Kit | MYST1 elisa kit

Human Probable histone acetyltransferase (MYST1) ELISA Kit

Gene Names
KAT8; MOF; hMOF; MYST1; ZC2HC8
Reactivity
Human
Synonyms
Probable histone acetyltransferase; Human Probable histone acetyltransferase (MYST1) ELISA Kit; MYST1 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of Human MYST1. No significant cross-reactivity or interference between Human MYST1 and analogues was observed.
Sequence Length
571
Samples
Serum, Plasma, Other biological fluids
Assay Type
Sandwich
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for MYST1 elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate MYST1 in samples. An antibody specific for MYST1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMYST1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MYST1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MYST1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,085 Da
NCBI Official Full Name
histone acetyltransferase KAT8 isoform 1
NCBI Official Synonym Full Names
lysine acetyltransferase 8
NCBI Official Symbol
KAT8
NCBI Official Synonym Symbols
MOF; hMOF; MYST1; ZC2HC8
NCBI Protein Information
histone acetyltransferase KAT8
UniProt Protein Name
Histone acetyltransferase KAT8
UniProt Gene Name
KAT8
UniProt Synonym Gene Names
MOF; MYST1; MYST-1; hMOF

NCBI Description

This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Uniprot Description

MYST1: Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Belongs to the MYST (SAS/MOZ) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Acetyltransferase; EC 2.3.1.48

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: histone acetyltransferase complex; kinetochore; nucleoplasm; nucleus

Molecular Function: acetyltransferase activity; enzyme binding; histone acetyltransferase activity; histone acetyltransferase activity (H4-K16 specific); metal ion binding; methylated histone residue binding; protein binding; transcription factor binding

Biological Process: histone acetylation; myeloid cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-templated; regulation of autophagy; transcription, DNA-dependent

Research Articles on MYST1

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Product Notes

The Human MYST1 kat8 (Catalog #AAA283181) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA283181 ELISA Kit recognizes Human MYST1. It is sometimes possible for the material contained within the vial of "Probable histone acetyltransferase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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