Rat myosin VB ELISA Kit | MYO5B elisa kit
Rat Myosin-Vb, MYO5B ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
3 sequence has high similarity to a putative mouse glutamic acid decarboxylase [RGD, Feb 2006]
Uniprot Description
MYO5B: May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis. Defects in MYO5B are a cause of diarrhea type 2 (DIAR2). DIAR2 is characterized by onset of intractable life- threatening watery diarrhea during infancy. Two forms are recognized: early-onset MVID with diarrhea beginning in the neonatal period, and late-onset, with first symptoms appearing after 3 or 4 months of life.
Protein type: Motility/polarity/chemotaxis; Motor
Cellular Component: neuron projection; protein complex; cell soma; apical cortex; perinuclear region of cytoplasm; dendritic spine; myosin complex
Molecular Function: calmodulin binding; ionotropic glutamate receptor binding; protein binding; motor activity; actin binding; ATP binding; Rab GTPase binding
Biological Process: vesicle-mediated transport; protein transport; regulation of protein localization; metabolic process; endosome localization
Research Articles on MYO5B
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Product Notes
The Rat MYO5B myo5b (Catalog #AAA9337084) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337084 ELISA Kit recognizes Rat MYO5B. It is sometimes possible for the material contained within the vial of "myosin VB, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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