Rat myosin regulatory light chain interacting protein ELISA Kit | MYLIP elisa kit
Rat E3 ubiquitin-protein ligase MYLIP, MYLIP ELISA Kit
Gene Names
Mylip; MIR
Reactivity
Rat
Synonyms
myosin regulatory light chain interacting protein; Rat E3 ubiquitin-protein ligase MYLIP; MYLIP ELISA Kit; Rat E3 ubiquitin-protein ligase MYLIP (MYLIP) ELISA kit; RP1-13D10.1; IDOL; MIR; band 4.1 superfamily member BZF1; cellular modulator of immune recognition (c-MIR) ; MYLIP elisa kit
Reactivity
Rat
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Samples
Human Body Fluids, Tissue Homogenates, Secretions Or Feces Samples
Assay Type
Quantitative Sandwich
Detection Range
0.625 ng/ml-20 ng/ml
Sensitivity
0.1 ng/ml.
Intra-assay Precision
Intra-assay CV (%) is less than 15%
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Related Product Information for MYLIP elisa kit
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of MYL4 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
49,890 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase MYLIP
NCBI Official Synonym Full Names
myosin regulatory light chain interacting protein
NCBI Official Symbol
Mylip
NCBI Official Synonym Symbols
MIR
NCBI Protein Information
E3 ubiquitin-protein ligase MYLIP; idol; inducible degrader of the LDL-receptor
UniProt Protein Name
E3 ubiquitin-protein ligase MYLIP
Protein Family
UniProt Gene Name
Mylip
UniProt Synonym Gene Names
Idol; MIR
UniProt Entry Name
MYLIP_RAT
Uniprot Description
Function: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR
Enzyme regulation: Can bind 1 iron ion per dimer. Iron binding seems to decrease LDLR degradation activity
Research Articles on MYLIP
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Product Notes
The Rat MYLIP mylip (Catalog #AAA9342673) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9342673 ELISA Kit recognizes Rat MYLIP. It is sometimes possible for the material contained within the vial of "myosin regulatory light chain interacting protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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