Myosin Light Chain 5 Recombinant Protein | MYL5 recombinant protein
Recombinant Human Myosin Light Chain 5 (1-173 a.a.)
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
Myosin Light Chain 5; Recombinant Human Myosin Light Chain 5 (1-173 a.a.); MYL5 (1-173 a.a.) Human; Myosin Light Chain 5 (1-173 a.a.) Human Recombinant; Myosin light chain 5; Myosin regulatory light chain 5; Superfast myosin regulatory light chain 2; MYLC2; MyLC-2; MYL5; MYL5 (1-173 a.a.); MYL5 recombinant protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
MYL5 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl,1mM DTT and 0.1mM PMSF.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMASRKT KKKEGGALRA QRASSNVFSN FEQTQIQEFK EAFTLMDQNR DGFIDKEDLK DTYASLGKTN VKDDELDAML KEASGPINFT MFLNLFGEKL SGTDAEETIL NAFKMLDPDG KGKINKEYIK RLLMSQADKM TAEEVDQMFQ FASIDVAGNLDYKALSYVIT HGEEKEE.
Sequence Length
173
Related Product Information for MYL5 recombinant protein
Introduction: Myosin regulatory light chain 5 (MYL5) is a hexameric ATPase cellular motor protein. Myosin is comprised of 2 heavy chains, 2 nonphosphorylatable alkali light chains, and 2 phosphorylatable regulatory light chains. MYL5 is a regulatory light chain and is expressed in the fetal muscle and in the adult retina, cerebellum, and basal ganglia. The reconstitution of myosin with MYL5 or alkali light chain increases filament velocity to intermediate rates, and the re-addition of both classes of light chains fully reinstates the original sliding pace.
Product Categories/Family for MYL5 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,888 Da
NCBI Official Full Name
myosin light chain 5
NCBI Official Synonym Full Names
myosin, light chain 5, regulatory
NCBI Official Symbol
MYL5
NCBI Protein Information
myosin light chain 5; MYLC2; myLC-2; myosin regulatory light chain 5; myosin, light polypeptide 5, regulatory; superfast myosin regulatory light chain 2
UniProt Protein Name
Myosin light chain 5
Protein Family
UniProt Gene Name
MYL5
UniProt Synonym Gene Names
MYLC2; MyLC-2
UniProt Entry Name
MYL5_HUMAN
NCBI Description
This gene encodes one of the myosin light chains, a component of the hexameric ATPase cellular motor protein myosin. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene product, one of the regulatory light chains, is expressed in fetal muscle and in adult retina, cerebellum, and basal ganglia. [provided by RefSeq, Jul 2008]
Uniprot Description
MYL5: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Contractile; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 4p16.3
Cellular Component: muscle myosin complex
Molecular Function: structural constituent of muscle; calcium ion binding
Biological Process: regulation of muscle contraction
Research Articles on MYL5
1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
