Typical Testing Data/Standard Curve (for reference only)
Human Microsomal triglyceride transfer protein large subunit ELISA Kit | MTTP elisa kit
Human Microsomal triglyceride transfer protein large subunit ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia. [provided by RefSeq, Jul 2008]
Uniprot Description
MTTP: Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B. Defects in MTTP are the cause of abetalipoproteinemia (ABL). ABL is an autosomal recessive disorder of lipoprotein metabolism. Affected individuals produce virtually no circulating apolipoprotein B-containing lipoproteins (chylomicrons, VLDL, LDL, lipoprotein(A)). Malabsorption of the antioxidant vitamin E occurs, leading to spinocerebellar and retinal degeneration.
Protein type: Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 4q24
Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; receptor complex
Molecular Function: lipid binding; lipid transporter activity; phospholipid transporter activity; protein binding; protein heterodimerization activity
Biological Process: lipid metabolic process; lipoprotein metabolic process; phospholipid transport; triacylglycerol transport
Disease: Abdominal Obesity-metabolic Syndrome 1; Abetalipoproteinemia
Research Articles on MTTP
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Product Notes
The Human MTTP mttp (Catalog #AAA2887563) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2887563 ELISA Kit recognizes Human MTTP. It is sometimes possible for the material contained within the vial of "Microsomal triglyceride transfer protein large subunit, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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