Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (Mthfd2) Recombinant Protein | Mthfd2 recombinant protein
Recombinant Mouse Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (Mthfd2)
Gene Names
Mthfd2; NMDMC; AW558851
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase; mitochondrial (Mthfd2); Recombinant Mouse Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Mthfd2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
36-350, Full length protein
Sequence
EAVVISGRKLAQQIKQEVQQEVEEWVASGNKRPHLSVILVGDNPASHSYVLNKTRAAAEVGINSETIVKPASVSEEELLNSIRKLNNDENVDGLLVQLPLPEHIDERKVCNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVQDPVTAKPKLVGDVDFEGVKKKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRPEELEVFKSKQRGVATN
Sequence Length
315
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Mthfd2 recombinant protein
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37,863 Da
NCBI Official Full Name
bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
NCBI Official Synonym Full Names
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
NCBI Official Symbol
Mthfd2
NCBI Official Synonym Symbols
NMDMC; AW558851
NCBI Protein Information
bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
UniProt Protein Name
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
UniProt Gene Name
Mthfd2
UniProt Synonym Gene Names
Nmdmc
Uniprot Description
Although its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency.
Research Articles on Mthfd2
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Product Notes
The Mthfd2 mthfd2 (Catalog #AAA954573) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 36-350, Full length protein. The amino acid sequence is listed below: EAVVISGRKL AQQIKQEVQQ EVEEWVASGN KRPHLSVILV GDNPASHSYV LNKTRAAAEV GINSETIVKP ASVSEEELLN SIRKLNNDEN VDGLLVQLPL PEHIDERKVC NAVSPDKDVD GFHVINVGRM CLDQYSMLPA TPWGVWEIIK RTGIPTLGKN VVVAGRSKNV GMPIAMLLHT DGAHERPGGD ATVTISHRYT PKEQLKKHTI LADIVISAAG IPNLITADMI KEGAAVIDVG INRVQDPVTA KPKLVGDVDF EGVKKKAGYI TPVPGGVGPM TVAMLMKNTI IAAKKVLRPE ELEVFKSKQR GVATN. It is sometimes possible for the material contained within the vial of "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (Mthfd2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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