Human Monofunctional C1-tetrahydrofolate synthase, mitochondrial ELISA Kit | MTHFD1L elisa kit

Human Monofunctional C1-tetrahydrofolate synthase, mitochondrial ELISA Kit

Cat. Num. AAA289706

• Gene Names: BHMT; BHMT1; HEL-S-61p
• Reactivity: Human
• Synonyms: Monofunctional C1-tetrahydrofolate synthase; mitochondrial; Human Monofunctional C1-tetrahydrofolate synthase; mitochondrial ELISA Kit; Betaine--homocysteine S-methyltransferase 1; BHMT; 2.1.1.5; MTHFD1L elisa kit

• Reactivity: Human
• Sequence Length: 406

• Assay Type: Sandwich
• Detection Range: 1.56-100 ng/mL
• Sensitivity: 0.12ng/ml
• Intra-Assay CV: <=6.4%
• Inter-Assay CV: <=10.3%
• Recovery: 111%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 157266337
• NCBI GeneID: 635
• NCBI Accession #: NP_001704.2
• NCBI GenBank Nucleotide #: NM_001713.2
• UniProt Accession #: Q93088; Q9UNI9
• Molecular Weight: 44,998 Da
• NCBI Official Full Name: betaine--homocysteine S-methyltransferase 1
• NCBI Official Synonym Full Names: betaine--homocysteine S-methyltransferase
• NCBI Official Symbol: BHMT
• NCBI Official Synonym Symbols: BHMT1; HEL-S-61p
• NCBI Protein Information: betaine--homocysteine S-methyltransferase 1
• UniProt Protein Name: Betaine--homocysteine S-methyltransferase 1
• Protein Family: Monofunctional C1-tetrahydrofolate synthase
• UniProt Gene Name: BHMT
• UniProt Entry Name: BHMT1_HUMAN

NCBI Description

This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed. [provided by RefSeq, Jul 2008]

Uniprot Description

BHMT: Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.

Protein type: Methyltransferase; EC 2.1.1.5; Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - glycine, serine and threonine

Chromosomal Location of Human Ortholog: 5q14.1

Cellular Component: cytoplasm; cytosol

Molecular Function: betaine-homocysteine S-methyltransferase activity; homocysteine S-methyltransferase activity; zinc ion binding

Biological Process: betaine catabolic process; betaine metabolic process; protein amino acid methylation; regulation of homocysteine metabolic process; S-adenosylmethionine metabolic process; sulfur amino acid metabolic process