Human musashi homolog 1 (Drosophila) ELISA Kit | MSI1 elisa kit

Human RNA-binding protein Musashi homolog 1, MSI1 ELISA Kit

Cat. Num. AAA9325045

• Reactivity: Human
• Synonyms: musashi homolog 1 (Drosophila); Human RNA-binding protein Musashi homolog 1; MSI1 ELISA Kit; Human RNA-binding protein Musashi homolog 1 (MSI1) ELISA kit; musashi 1; MSI1 elisa kit

• Reactivity: Human

• Assay Type: Quantitative Sandwich
• Detection Range: 0.625ng/ml-20ng/ml
• Sensitivity: 0.1ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for MSI1 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of MSI1 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 4505255
• NCBI GeneID: 4440
• NCBI Accession #: NP_002433.1
• NCBI GenBank Nucleotide #: NM_002442.3
• UniProt Accession #: O43347; Q96PU0; Q96PU1; Q96PU2; Q96PU3
• Molecular Weight: 39,125 Da
• NCBI Official Full Name: RNA-binding protein Musashi homolog 1
• NCBI Official Synonym Full Names: musashi RNA-binding protein 1
• NCBI Official Symbol: MSI1
• NCBI Protein Information: RNA-binding protein Musashi homolog 1; musashi1; musashi-1
• UniProt Protein Name: RNA-binding protein Musashi homolog 1
• Protein Family: RNA-binding protein
• UniProt Gene Name: MSI1
• UniProt Synonym Gene Names: Musashi-1
• UniProt Entry Name: MSI1H_HUMAN

NCBI Description

This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008]

Uniprot Description

Musashi-1: RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. Belongs to the Musashi family.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 12q24

Cellular Component: polysome; cytoplasm; nucleus

Molecular Function: RNA binding; nucleotide binding; poly(U) binding

Biological Process: nervous system development; epithelial cell differentiation; response to hormone stimulus