DNA-3-methyladenine glycosylase Recombinant Protein | 3MG recombinant protein
Recombinant Human DNA-3-methyladenine glycosylase
Gene Names
MPG; AAG; MDG; ADPG; APNG; Mid1; anpg; PIG11; PIG16; CRA36.1
Reactivity
Human
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
DNA-3-methyladenine glycosylase; Recombinant Human DNA-3-methyladenine glycosylase; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; ADPGN-methylpurine-DNA glycosylase; 3MG recombinant protein
Host
Yeast
Reactivity
Human
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
20mM Tris-HCl based buffer, pH8.0
Sequence Positions
Partial of the Full Length of 1-298aa, 13-298aa
Tag Info
His-tag
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for 3MG recombinant protein
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34.2kD
NCBI Official Full Name
DNA-3-methyladenine glycosylase isoform b
NCBI Official Synonym Full Names
N-methylpurine DNA glycosylase
NCBI Official Symbol
MPG
NCBI Official Synonym Symbols
AAG; MDG; ADPG; APNG; Mid1; anpg; PIG11; PIG16; CRA36.1
NCBI Protein Information
DNA-3-methyladenine glycosylase
UniProt Protein Name
DNA-3-methyladenine glycosylase
Protein Family
UniProt Gene Name
MPG
UniProt Synonym Gene Names
AAG; ANPG; MID1
Uniprot Description
MPG: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. Belongs to the DNA glycosylase MPG family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.2.2.21; Hydrolase; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: nucleoplasm
Molecular Function: alkylbase DNA N-glycosylase activity; damaged DNA binding; DNA N-glycosylase activity; protein binding
Biological Process: base-excision repair; depurination; DNA dealkylation
Research Articles on 3MG
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Product Notes
The 3MG mpg (Catalog #AAA9422401) is a Recombinant Protein produced from Yeast and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Partial of the Full Length of 1-298aa, 13-298aa. The Recombinant Human DNA-3-methyladenine glycosylase reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "DNA-3-methyladenine glycosylase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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