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Alpha-1 Acid Glycoprotein | A1AG protein

Mouse Serum ALPHA-1-ACID GLYCOPROTEIN

Purity
>95% (SDS-PAGE)
Synonyms
Alpha-1 Acid Glycoprotein; Mouse Serum ALPHA-1-ACID GLYCOPROTEIN; Alpha-1 Acid Glycoprotein (A1AG); Mouse; A1AG protein
Ordering
For Research Use Only!
Host
Mouse Serum
Purity/Purification
>95% (SDS-PAGE)
Form/Format
Frozen Liquid
Sequence Length
201
Protein
1.36 mg/mL (Radial Immunodiffusion Assay)
Note
Mouse alpha-1-Acid Glycoprotein is one of the most acidic proteins found in serum. It has a molecular weight of approximately 40kDa with a high (~45%) content of carbohydrate. It is a positive acute phase reactant, the levels of which increase significantly in mice in response to inflammation tissue injury or disease.
Recertification
9-25-2016
Recovery
Mricrofuge vial before drawing from container.
Preparation and Storage
At -20 degree C
Related Product Information for A1AG protein
MyBioSource produces Alpha-1 Acid Glycoprotein for clinical research and bulk clinical manufacturing.

Technical support, bulk quantities and aliquoting available.

Alpha-1 Acid Glycoprotein (a1AG; AGP) is an Acute Phase protein. Reduced serum Alpha-1 Acid Glycoprotein levels are mainly associated with impaired liver function but can also occur in vitamin A deficiency and conditions in which protein is being lost from the blood. AGP increased level (in parallel to increases in haptoglobin) is suggestive of inflammation. a1AG levels rise before those of haptoglobin therefore this test can be useful in determining the chronology of inflammatory processes.

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
~40 kDa
NCBI Official Full Name
alpha-1 acid glycoprotein
UniProt Protein Name
Alpha-1-acid glycoprotein 1
UniProt Gene Name
ORM1
UniProt Synonym Gene Names
AGP1; AGP 1; OMD 1
UniProt Entry Name
A1AG1_HUMAN

Uniprot Description

ORM1: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Belongs to the calycin superfamily. Lipocalin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q32

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding

Biological Process: regulation of immune system process; transport; acute-phase response; inflammatory response

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Product Notes

The A1AG orm1 (Catalog #AAA173352) is a Protein produced from Mouse Serum and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Alpha-1 Acid Glycoprotein, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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