Mouse Thrombin Activatable Fibrinolysis Inhibitor (TAFI) RTU ELISA Kit | TAFI rtu elisa kit

Mouse Thrombin Activatable Fibrinolysis Inhibitor (TAFI) ELISA Kit

Cat. Num. AAA4502723

• Gene Names: Cpb2; CPR; Cpu; TAFI; AI255929; 1110032P04Rik; 4930405E17Rik
• Reactivity: Mouse
• Synonyms: Thrombin Activatable Fibrinolysis Inhibitor (TAFI); Mouse Thrombin Activatable Fibrinolysis Inhibitor (TAFI) ELISA Kit; CPB2; CPU; PCPB; Carboxypeptidase B2; Plasma Carboxypeptidase B; Carboxypeptidase U; TAFI rtu elisa kit

• Reactivity: Mouse
• Sequence Length: 422

• Assay Type: Sandwich
• Samples: Plasma.
• Detection Range: 0.781-50ng/mL
• Sensitivity: 0.32ng/mL
• RTU ELISA Kit's Advantage: The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
• Preparation and Storage: For unopened kits: All the reagents should be kept at 4 degree C upon receipt.; For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for TAFI rtu elisa kit

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to TAFI. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to TAFI. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain TAFI, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of TAFI in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 31982712
• NCBI GeneID: 56373
• NCBI Accession #: NP_062749.2
• NCBI GenBank Nucleotide #: NM_019775.3
• UniProt Accession #: Q9JHH6; Q5EBI3; Q9QZF0
• Molecular Weight: 48,871 Da
• NCBI Official Full Name: carboxypeptidase B2 preproprotein
• NCBI Official Synonym Full Names: carboxypeptidase B2 (plasma)
• NCBI Official Symbol: Cpb2
• NCBI Official Synonym Symbols: CPR; Cpu; TAFI; AI255929; 1110032P04Rik; 4930405E17Rik
• NCBI Protein Information: carboxypeptidase B2
• UniProt Protein Name: Carboxypeptidase B2
• UniProt Gene Name: Cpb2
• UniProt Synonym Gene Names: Tafi; CPR; CPU; TAFI

NCBI Description

This gene encodes carboxypeptidase B, a zinc-dependent metalloprotease that cleaves peptide bonds at the C-terminus of protein substrates. The encoded preproprotein undergoes proteolytic activation to generate a mature, functional enzyme, and secreted into plasma. [provided by RefSeq, Jan 2016]

Uniprot Description

Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.