Mouse Interleukin 11 (IL11) RTU ELISA Kit | IL11 rtu elisa kit

Mouse Interleukin 11 (IL11) ELISA Kit

Cat. Num. AAA4500180

• Gene Names: Il11; IL-11
• Reactivity: Mouse
• Synonyms: Interleukin 11 (IL11); Mouse Interleukin 11 (IL11) ELISA Kit; AGIF; Adipogenesis Inhibitory Factor; Oprelvekin; IL11 rtu elisa kit

• Reactivity: Mouse
• Sequence Length: 199

• Assay Type: Sandwich
• Samples: Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates or Other Biological Fluids.
• Detection Range: 15.6-1000pg/mL
• Sensitivity: 7.1pg/mL
• RTU ELISA Kit's Advantage: The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
• Preparation and Storage: For unopened kits: All the reagents should be kept at 4 degree C upon receipt.; For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for IL11 rtu elisa kit

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to IL11. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to IL11. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain IL11, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of IL11 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 6680393
• NCBI GeneID: 16156
• NCBI Accession #: NP_032376.1
• NCBI GenBank Nucleotide #: NM_008350.4
• UniProt Accession #: P47873
• Molecular Weight: 21,522 Da
• NCBI Official Full Name: interleukin-11 isoform 1
• NCBI Official Synonym Full Names: interleukin 11
• NCBI Official Symbol: Il11
• NCBI Official Synonym Symbols: IL-11
• NCBI Protein Information: interleukin-11
• UniProt Protein Name: Interleukin-11
• Protein Family: Interleukin
• UniProt Gene Name: Il11
• UniProt Synonym Gene Names: IL-11

Uniprot Description

Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:8913282). Also promotes the proliferation of hepatocytes in response to liver damage (PubMed:22253262). Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation, also in the context of various cancers (PubMed:10026196, PubMed:23948300). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3 (PubMed:23948300, PubMed:22253262).