Testing Data
anti-Mouse, Rat NPY Y2 Receptor Antibody | anti-NPY Y2 antibody
NPY Y2 Receptor, Control Peptide
Testing Data
Testing Data
Testing Data
Testing Data
NCBI and Uniprot Product Information
Uniprot Description
NPY2R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 4q31
Cellular Component: integral to plasma membrane; nonmotile primary cilium; plasma membrane
Molecular Function: peptide YY receptor activity; protein binding; calcium channel regulator activity; neuropeptide Y receptor activity; receptor activity
Biological Process: positive regulation of dopamine secretion; secretion; positive regulation of cell adhesion; behavioral fear response; negative regulation of synaptic transmission, glutamatergic; locomotory behavior; positive regulation of peptide secretion; elevation of cytosolic calcium ion concentration; negative regulation of cAMP biosynthetic process; neuropeptide signaling pathway; negative regulation of secretion; regulation of sensory perception of pain; G-protein signaling, adenylate cyclase inhibiting pathway; positive regulation of smooth muscle contraction; negative regulation of neurological process; positive regulation of circadian sleep/wake cycle, non-REM sleep; nitric oxide mediated signal transduction
Research Articles on NPY Y2
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Product Notes
The NPY Y2 npy2r (Catalog #AAA555329) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The NPY Y2 Receptor, Control Peptide reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NPY Y2 Receptor can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB). Used for absorption control of antiserum binding. Antibody should be pre-incubated withpeptide prior to incubation with tissue/sample. We suggest pre-Incubation for 1 hour at room temperature. A 10-6 or 105 molar (M) peptide concentration is suggested to block antigentibody binding. However, optimal working concentration should be determined by the investigator using a range of peptide dilutions to eliminate or reduce immunoreactivity. Researchers should empirically determine the suitability of the NPY Y2 npy2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: TDSFSEATNV. It is sometimes possible for the material contained within the vial of "NPY Y2 Receptor, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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