Western Blot (WB)
(Figure 1: Western blot analysis using TAB2 mAb against HEK293 (1) and TAB2-hIgGFc transfected HEK293 (2) cell lysate.)
Mouse anti-Human, Rat TAB2 Antibody | anti-TAB2 antibody
TAB2 Antibody
FC: 1:200-1:400
ELISA: 1:10000
Western Blot (WB)
(Figure 1: Western blot analysis using TAB2 mAb against HEK293 (1) and TAB2-hIgGFc transfected HEK293 (2) cell lysate.)
Western Blot (WB)
(Figure 1: Western blot analysis using TAB2 mAb against HEK293 (1) and TAB2-hIgGFc transfected HEK293 (2) cell lysate.)
Flow Cytometry (FC/FACS)
(Figure 2: Flow cytometric analysis of HL-60 cells using TAB2 mouse mAb (green) and negative control (purple).)
Flow Cytometry (FC/FACS)
(Figure 2: Flow cytometric analysis of HL-60 cells using TAB2 mouse mAb (green) and negative control (purple).)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Uniprot Description
Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
Research Articles on TAB2
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Product Notes
The TAB2 tab2 (Catalog #AAA850652) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TAB2 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TAB2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Flow Cytometry (FC/FACS), ELISA (EIA). WB: 1:500-1:2000 FC: 1:200-1:400 ELISA: 1:10000. Researchers should empirically determine the suitability of the TAB2 tab2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAB2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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