Mouse anti-Human CA 19-9 Antibody | anti-CA 19-9 antibody
CA 19-9, Sialyl-Lewis a
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Synonyms
CA 19-9; Sialyl-Lewis a; anti-CA 19-9 antibody
Host
Mouse
Reactivity
Human
Isotype
IgM
Clone Number
121 SLE
Form/Format
Solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide.
Concentration
50 ug/ml (varies by lot)
Applicable Applications for anti-CA 19-9 antibody
ELISA, Immunoradiometric assay (IRMA), Immunohistochemistry (IHC) Formalin/Paraffin
Application Notes
Dilution: 1:10-1:50
Immunogen
Immunodiffusion precipitate of ovarian cystic mucins with NS19-9-antibody
Positive Control
Colon carcinoma
Incubation Time
60 min at RT
Pre-Treatment
In paraffin section no pre-treatment is required, however heat induced antigen retrieval may improve the staining. Each laboratory should select it's own optimum staining and pre-treatment conditions.
Pre-Treatment
In paraffin section no pre-treatment is required, however heat induced antigen retrieval may improve the staining. Each laboratory should select it's own optimum staining and pre-treatment conditions.
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-CA 19-9 antibody
CA 19-9 antibody reacts strongly positive with most tumour cell lines of gastrointestinal carcinoma including adenocarcinoma of the stomach, intestine, and pancreas. Positive reactivity was also found in transitional cell carcinoma of the bladder, adenocarcinoma of the endometrium and the gallbladder as well as in papillary carcinoma of the thyroid glands. Last but not least positive reactivity of lung carcinoma must be mentioned (adenocarcinoma, bronchio-alveolar carcinoma, squamous epithelial carcinoma, and SCLC). Sialyl Lewis a antigen is an oncofetal antigen, which appears during early development of the gastrointestinal tract. After birth it is still detectable in ductus and secretion of intestinal glands, respiratory and reproductive tract. In normal tissue Sialyl Lewis a (CA 19-9) is found in ductal epithelia of the breast, kidney, salivary glands, lung, colon, bile duct, liver, pancreas and prostate gland. Sialyl Lewis a antigen (Cancer Antigen CA 19-9).
References
1. Gatalica Z., and Miettienen M. (1994) Distribution of carcinoma antigens CA 19-9 and CA 15-3: an immunohistochemical study of 400 tumors. Appl. Immunohistochem. 2(3); 205ff. 2. Tomazic A., and Pegan V. (2000) Preoperative staging of periampullar cancer with US, CT, EUS and CA 19-9. Hepatogastroenterol. 47(34); 1135-1137. 3. Tabata T., Takeshima N., Tanaka N., Hirai Y., and Hasumi K. (2000) Clinical value of tumor markers for early detection of recurrence in patients with cervical adenocarcinoma and adenosquamous carcinoma. Tumour Biol. 21(6); 375-380. 4. Dalgleish A.G. (2000) Tumour markers in malignancies. CA19.9 is useful in several cancers. B.M.J. 321(7257); 380.
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Product Notes
The CA 19-9 (Catalog #AAA397038) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CA 19-9, Sialyl-Lewis a reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CA 19-9 can be used in a range of immunoassay formats including, but not limited to, ELISA, Immunoradiometric assay (IRMA), Immunohistochemistry (IHC) Formalin/Paraffin. Dilution: 1:10-1:50. Researchers should empirically determine the suitability of the CA 19-9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CA 19-9, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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