Mouse Wnt-3a ELISA Kit | Wnt-3a elisa kit
Mouse Protein Wnt-3a ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
WNT3A: Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube. Interacts with PORCN. Interacts with APCDD1 and WLS. Component of the Wnt-Fzd-LRP5-LRP6 signaling complex that contains a WNT protein, a FZD protein and LRP5 or LRP6. Interacts directly in the complex with LRP6. Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate. Belongs to the Wnt family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11 B1.3|11 37.17 cM
Cellular Component: cell surface; extracellular space
Molecular Function: frizzled binding; frizzled-2 binding; protein binding; protein domain specific binding; receptor agonist activity; receptor binding; transcription coactivator activity
Biological Process: anterior/posterior pattern formation; axon guidance; axonogenesis; BMP signaling pathway; cell proliferation in forebrain; cell proliferation in midbrain; cell-cell signaling; determination of left/right symmetry; dorsoventral neural tube patterning; extracellular matrix organization and biogenesis; heart looping; hemopoiesis; hippocampus development; in utero embryonic development; inner ear morphogenesis; mammary gland development; mesoderm development; midbrain development; negative regulation of axon extension involved in axon guidance; negative regulation of fat cell differentiation; negative regulation of neurogenesis; neurogenesis; organ morphogenesis; osteoblast differentiation; palate development; paraxial mesodermal cell fate commitment; platelet activation; positive regulation of B cell proliferation; positive regulation of caspase activity; positive regulation of cell proliferation; positive regulation of collateral sprouting in the absence of injury; positive regulation of cytokine production; positive regulation of mesodermal cell fate specification; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein amino acid phosphorylation; positive regulation of protein binding; positive regulation of protein kinase activity; positive regulation of receptor internalization; positive regulation of skeletal muscle development; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of axonogenesis; regulation of cell differentiation; signal transduction; signalosome assembly; somatic stem cell division; somitogenesis; spinal cord association neuron differentiation; Wnt receptor signaling pathway; Wnt receptor signaling pathway in forebrain neuroblast division; Wnt receptor signaling pathway through beta-catenin
Research Articles on Wnt-3a
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Product Notes
The Mouse Wnt-3a wnt3a (Catalog #AAA9428190) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9428190 ELISA Kit recognizes Mouse Wnt-3a. It is sometimes possible for the material contained within the vial of "Wnt-3a, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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