Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse VPS10 domain-containing receptor SorCS1 (SORCS1) Standard Curve.)
Mouse VPS10 Domain-Containing Receptor SorCS1 (SORCS1) ELISA Kit | SORCS1 elisa kit
Mouse VPS10 Domain-Containing Receptor SorCS1 (SORCS1) ELISA Kit
Reactivity
Mouse
Synonyms
VPS10 Domain-Containing Receptor SorCS1 (SORCS1); Mouse VPS10 Domain-Containing Receptor SorCS1 (SORCS1) ELISA Kit; SORCS1; RP11-446H13.1; FLJ41758; FLJ43475; FLJ44957; SORCS receptor 1; VPS10 domain receptor SorCS; VPS10 domain receptor protein SORCS 1; SORCS1 elisa kit
Reactivity
Mouse
Specificity
Mouse VPS10 domain-containing receptor SorCS1 (SORCS1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SORCS1. No significant cross-reactivity or interference between Mouse SORCS1 and analogues was observed.
Sequence Length
1168
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse VPS10 domain-containing receptor SorCS1 (SORCS1) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse VPS10 domain-containing receptor SorCS1 (SORCS1) Standard Curve.)
Related Product Information for SORCS1 elisa kit
Description: This Mouse VPS10 domain-containing receptor SorCS1 (SORCS1) ELISA Kit employs a two-site sandwich ELISA to quantitate SORCS1 in samples. An antibody specific for SORCS1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SORCS1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SORCS1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SORCS1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: SORCS1 encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified.
Background: SORCS1 encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
VPS10 domain-containing receptor SorCS1 isoform 1
UniProt Protein Name
VPS10 domain-containing receptor SorCS1
Protein Family
UniProt Gene Name
Sorcs1
UniProt Synonym Gene Names
Sorcs; mSorCS
UniProt Entry Name
SORC1_MOUSE
Uniprot Description
Subcellular location: Membrane; Single-pass type I membrane protein.
Tissue specificity: Isoform 1 is highly expressed in brain, and at lower levels in heart, liver and kidney. Detected in newborn brain and in adult olfactory bulb and cerebral cortex. Isoform 2 is highly expressed in liver, and at lower levels in heart, brain, kidney and testis.
Sequence similarities: Belongs to the VPS10-related sortilin family. SORCS subfamily.Contains 5 BNR repeats.Contains 1 PKD domain.
Sequence caution: The sequence AAH07486.1 differs from that shown. Reason: Frameshift at position 472.
Similar Products
Product Notes
The Mouse SORCS1 sorcs1 (Catalog #AAA9717015) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717015 ELISA Kit recognizes Mouse SORCS1. It is sometimes possible for the material contained within the vial of "VPS10 Domain-Containing Receptor SorCS1 (SORCS1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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