Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human VPS10 domain-containing receptor SorCS3 (SORCS3) Standard Curve.)
Human VPS10 Domain-Containing Receptor SorCS3 (SORCS3) ELISA Kit | SORCS3 elisa kit
Human VPS10 Domain-Containing Receptor SorCS3 (SORCS3) ELISA Kit
Gene Names
SORCS3; SORCS
Reactivity
Human
Synonyms
VPS10 Domain-Containing Receptor SorCS3 (SORCS3); Human VPS10 Domain-Containing Receptor SorCS3 (SORCS3) ELISA Kit; SORCS3; RP11-107L7.1; SORCS; 6330404A12Rik; VPS10 domain receptor protein SORCS 3; VPS10 domain receptor protein SORCS 3 (SORCS3); SORCS3 elisa kit
Reactivity
Human
Specificity
Human VPS10 domain-containing receptor SorCS3 (SORCS3) ELISA Kit has high sensitivity and excellent specificity for detection of Human SORCS3. No significant cross-reactivity or interference between Human SORCS3 and analogues was observed.
Sequence Length
1222
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human VPS10 domain-containing receptor SorCS3 (SORCS3) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human VPS10 domain-containing receptor SorCS3 (SORCS3) Standard Curve.)
Related Product Information for SORCS3 elisa kit
Description: This Human VPS10 domain-containing receptor SorCS3 (SORCS3) ELISA Kit employs a two-site sandwich ELISA to quantitate SORCS3 in samples. An antibody specific for SORCS3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SORCS3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SORCS3 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SORCS3 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: SORCS3 encodes a type-I receptor transmembrane protein that is a member of the vacuolar protein sorting 10 receptor family. Proteins of this family are defined by a vacuolar protein sorting 10 domain at the N-terminus. The N-terminal segment of this domain has a consensus motif for proprotein convertase processing, and the C-terminal segment of this domain is characterized by ten conserved cysteine residues. The vacuolar protein sorting 10 domain is followed by a leucine-rich segment, a transmembrane domain, and a short C-terminal cytoplasmic domain that interacts with adaptor molecules. The transcript is expressed at high levels in the brain, and candidate gene studies suggest that genetic variation in this gene is associated with Alzheimer's disease. Consistent with this observation, knockdown of SORCS3 in cell culture results in an increase in amyloid precursor protein processing.
Background: SORCS3 encodes a type-I receptor transmembrane protein that is a member of the vacuolar protein sorting 10 receptor family. Proteins of this family are defined by a vacuolar protein sorting 10 domain at the N-terminus. The N-terminal segment of this domain has a consensus motif for proprotein convertase processing, and the C-terminal segment of this domain is characterized by ten conserved cysteine residues. The vacuolar protein sorting 10 domain is followed by a leucine-rich segment, a transmembrane domain, and a short C-terminal cytoplasmic domain that interacts with adaptor molecules. The transcript is expressed at high levels in the brain, and candidate gene studies suggest that genetic variation in this gene is associated with Alzheimer's disease. Consistent with this observation, knockdown of SORCS3 in cell culture results in an increase in amyloid precursor protein processing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
VPS10 domain-containing receptor SorCS3
NCBI Official Synonym Full Names
sortilin related VPS10 domain containing receptor 3
NCBI Official Symbol
SORCS3
NCBI Official Synonym Symbols
SORCS
NCBI Protein Information
VPS10 domain-containing receptor SorCS3
UniProt Protein Name
VPS10 domain-containing receptor SorCS3
Protein Family
UniProt Gene Name
SORCS3
UniProt Synonym Gene Names
KIAA1059
UniProt Entry Name
SORC3_HUMAN
NCBI Description
This gene encodes a type-I receptor transmembrane protein that is a member of the vacuolar protein sorting 10 receptor family. Proteins of this family are defined by a vacuolar protein sorting 10 domain at the N-terminus. The N-terminal segment of this domain has a consensus motif for proprotein convertase processing, and the C-terminal segment of this domain is characterized by ten conserved cysteine residues. The vacuolar protein sorting 10 domain is followed by a leucine-rich segment, a transmembrane domain, and a short C-terminal cytoplasmic domain that interacts with adaptor molecules. The transcript is expressed at high levels in the brain, and candidate gene studies suggest that genetic variation in this gene is associated with Alzheimer's disease. Consistent with this observation, knockdown of the gene in cell culture results in an increase in amyloid precursor protein processing. [provided by RefSeq, Dec 2014]
Research Articles on SORCS3
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Product Notes
The Human SORCS3 sorcs3 (Catalog #AAA9714224) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714224 ELISA Kit recognizes Human SORCS3. It is sometimes possible for the material contained within the vial of "VPS10 Domain-Containing Receptor SorCS3 (SORCS3), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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