Mouse Visfatin (VF) ELISA Kit | VF elisa kit

Mouse Visfatin (VF) ELISA Kit

Cat. Num. AAA452579

• Gene Names: Nampt; Pbef; Pbef1; AI314458; AI480535; Visfatin; NAmPRTase; 1110035O14Rik
• Reactivity: Mouse
• Synonyms: Visfatin (VF); Mouse Visfatin (VF) ELISA Kit; Nampt; NAmPRTase; PBEF; PBEF1; Pre-B-Cell Colony Enhancing Factor; Nicotinamide Phosphoribosyltransferase; VF elisa kit

• Reactivity: Mouse
• Sequence Length: 491

• Samples: Serum, plasma and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 31.25-2000pg/mL
• Sensitivity: 13.2pg/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 257153454
• NCBI GeneID: 59027
• NCBI Accession #: NP_067499.2
• NCBI GenBank Nucleotide #: NM_021524.2
• UniProt Accession #: Q99KQ4; Q8C3B5; Q9JKM0
• Molecular Weight: 55,447 Da
• NCBI Official Full Name: nicotinamide phosphoribosyltransferase
• NCBI Official Synonym Full Names: nicotinamide phosphoribosyltransferase
• NCBI Official Symbol: Nampt
• NCBI Official Synonym Symbols: Pbef; Pbef1; AI314458; AI480535; Visfatin; NAmPRTase; 1110035O14Rik
• NCBI Protein Information: nicotinamide phosphoribosyltransferase
• UniProt Protein Name: Nicotinamide phosphoribosyltransferase
• UniProt Gene Name: Nampt
• UniProt Synonym Gene Names: Pbef1; NAmPRTase; Nampt; PBEF

Uniprot Description

The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma (). Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.