Mouse Tryptophan Hydroxylase 1 (TPH1) ELISA Kit | TPH1 elisa kit

Mouse Tryptophan Hydroxylase 1 (TPH1) ELISA Kit

Cat. Num. AAA453713

• Gene Names: Tph1; Tph
• Reactivity: Mouse
• Synonyms: Tryptophan Hydroxylase 1 (TPH1); Mouse Tryptophan Hydroxylase 1 (TPH1) ELISA Kit; TPH; TPRH; TRPH; Tryptophan 5-Monooxygenase; TPH1 elisa kit

• Reactivity: Mouse
• Specificity: This assay has high sensitivity and excellent specificity for detection of TPH1. No significant cross-reactivity or interference between TPH1 and analogues was observed.
• Sequence Length: 447

• Samples: mouse tissue homogenates, cell lysates or other biological fluids
• Detection Range: 0.156-10ng/mL
• Sensitivity: <0.054ng/mL
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level TPH1 were tested 20 times on one plate, respectively. Intra-Assay: CV<10%
• Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level TPH1 were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for TPH1 elisa kit

Intended Uses: The kit is a sandwich enzyme immunoassay for the in vitro quantitative measurement of TPH1 in mouse tissue homogenates, cell lysates or other biological fluids.

NCBI and Uniprot Product Information

• NCBI GI #: 209862985
• NCBI GeneID: 21990
• NCBI Accession #: NP_001129556.1
• NCBI GenBank Nucleotide #: NM_001136084.2
• UniProt Accession #: P17532
• Molecular Weight: 51,343 Da
• NCBI Official Full Name: tryptophan 5-hydroxylase 1 isoform 1
• NCBI Official Synonym Full Names: tryptophan hydroxylase 1
• NCBI Official Symbol: Tph1
• NCBI Official Synonym Symbols: Tph
• NCBI Protein Information: tryptophan 5-hydroxylase 1
• UniProt Protein Name: Tryptophan 5-hydroxylase 1
• Protein Family: Tryptophan 5-hydroxylase
• UniProt Gene Name: Tph1
• UniProt Synonym Gene Names: Tph

NCBI Description

This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase family. The encoded protein is one of two tryptophan hydroxylase enzymes that catalyze the first and rate limiting step in the biosynthesis of the hormone and neurotransmitter, serotonin. This gene is expressed in peripheral organs, while tryptophan hydroxylase 2 is expressed in neurons. The encoded protein is involved in the development of hypoxia-induced elevations in pulmonary pressures and pulmonary vascular remodeling, and has also been implicated as a regulator of immune tolerance. Disruption of this gene is associated with cardiac dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]