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Mouse tissue inhibitors of metalloproteinase 1, TIMP-1 ELISA Kit | TIMP-1 elisa kit

Mouse tissue inhibitors of metalloproteinase 1, TIMP-1 ELISA Kit

Gene Names
Timp1; EPA; Clgi; Timp; TIMP-1; TPA-S1
Reactivity
Mouse
Synonyms
tissue inhibitors of metalloproteinase 1; TIMP-1; Mouse tissue inhibitors of metalloproteinase 1; TIMP-1 ELISA Kit; RP1-230G1.3; CLGI; EPA; EPO; FLJ90373; HCI; TIMP; erythroid potentiating activity; fibroblast collagenase inhibitor; tissue inhibitor of metalloproteinase 1; TIMP1; TIMP metallopeptidase inhibitor 1; TIMP-1 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Samples
Serum, Plasma and Cell culture supernates
Detection Range
0.156 ng/mL-10 ng/mL
Sensitivity
0.110 ng/ml
Sample Volume
50-100ul
Detection Wavelength
450 nm
Preparation and Storage
Store at 4 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,628 Da
NCBI Official Full Name
metalloproteinase inhibitor 1 isoform a
NCBI Official Synonym Full Names
tissue inhibitor of metalloproteinase 1
NCBI Official Symbol
Timp1
NCBI Official Synonym Symbols
EPA; Clgi; Timp; TIMP-1; TPA-S1
NCBI Protein Information
metalloproteinase inhibitor 1
UniProt Protein Name
Metalloproteinase inhibitor 1
UniProt Gene Name
Timp1
UniProt Synonym Gene Names
Timp; Timp-1; EPA; TIMP-1

Uniprot Description

TIMP1: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14. Belongs to the protease inhibitor I35 (TIMP) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: X A1.3|X 16.38 cM

Cellular Component: basement membrane; extracellular matrix; extracellular space; proteinaceous extracellular matrix

Molecular Function: cytokine activity; metalloendopeptidase inhibitor activity; protease binding

Biological Process: cell activation; negative regulation of apoptosis; negative regulation of catalytic activity; negative regulation of membrane protein ectodomain proteolysis; positive regulation of cell proliferation; response to cytokine stimulus; response to hormone stimulus

Research Articles on TIMP-1

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Product Notes

The Mouse TIMP-1 timp1 (Catalog #AAA9424707) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9424707 ELISA Kit recognizes Mouse TIMP-1. It is sometimes possible for the material contained within the vial of "tissue inhibitors of metalloproteinase 1, TIMP-1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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