Mouse Synaptotagmin-5 (SYT5) ELISA Kit | SYT5 elisa kit
Mouse Synaptotagmin-5 (SYT5) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Background: Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules.
NCBI and Uniprot Product Information
Uniprot Description
SYT5: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)- dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface. Belongs to the synaptotagmin family.
Protein type: Membrane protein, integral
Cellular Component: neuron projection; cell soma; membrane; synaptic vesicle membrane; perinuclear region of cytoplasm; plasma membrane; integral to membrane; synapse; cytoplasmic vesicle; cell junction; endosome
Molecular Function: clathrin binding; syntaxin binding; calcium-dependent phospholipid binding; protein heterodimerization activity; metal ion binding; calcium ion binding
Biological Process: vesicle fusion; synaptic vesicle exocytosis; calcium ion-dependent exocytosis of neurotransmitter; synaptic vesicle endocytosis; regulation of calcium ion-dependent exocytosis; calcium ion-dependent exocytosis
Research Articles on SYT5
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Product Notes
The Mouse SYT5 syt5 (Catalog #AAA9716915) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9716915 ELISA Kit recognizes Mouse SYT5. It is sometimes possible for the material contained within the vial of "Synaptotagmin-5 (SYT5), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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