Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Soluble endothelial protein C receptor (sEPCR) Standard Curve.)
Mouse Soluble Endothelial Protein C Receptor (sEPCR) ELISA Kit | sEPCR elisa kit
Mouse Soluble Endothelial Protein C Receptor (sEPCR) ELISA Kit
Gene Names
Procr; Ccca; Epcr; Ccd41; AI325044
Reactivity
Mouse
Synonyms
Soluble Endothelial Protein C Receptor (sEPCR); Mouse Soluble Endothelial Protein C Receptor (sEPCR) ELISA Kit; PROCR; CCCA; CCD41; CD201; EPCR; MGC23024; bA42O4.2; APC receptor; CD201 antigen; OTTHUMP00000030729; activated protein C receptor; cell cycle; centrosome-associated protein; centrocyclin; endothelial protein C; sEPCR elisa kit
Reactivity
Mouse
Specificity
Mouse Soluble endothelial protein C receptor (sEPCR) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PROCR. No significant cross-reactivity or interference between Mouse PROCR and analogues was observed.
Sequence Length
242
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Soluble endothelial protein C receptor (sEPCR) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Soluble endothelial protein C receptor (sEPCR) Standard Curve.)
Related Product Information for sEPCR elisa kit
Description: This Mouse Soluble endothelial protein C receptor (sEPCR) ELISA Kit employs a two-site sandwich ELISA to quantitate PROCR in samples. An antibody specific for PROCR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PROCR present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PROCR is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PROCR bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: Endothelial protein C receptor (EPCR) also known as activated protein C receptor (APC receptor) is a protein that in humans is encoded by the PROCR gene.PROCR has also recently been designated CD201 (cluster of differentiation 201). The protein encoded by this gene is a receptor for protein C that enhances its activation. Protein C is an anti-coagulant serine protease activated by the blood coagulation pathway.
Background: Endothelial protein C receptor (EPCR) also known as activated protein C receptor (APC receptor) is a protein that in humans is encoded by the PROCR gene.PROCR has also recently been designated CD201 (cluster of differentiation 201). The protein encoded by this gene is a receptor for protein C that enhances its activation. Protein C is an anti-coagulant serine protease activated by the blood coagulation pathway.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
endothelial protein C receptor
NCBI Official Synonym Full Names
protein C receptor, endothelial
NCBI Official Symbol
Procr
NCBI Official Synonym Symbols
Ccca; Epcr; Ccd41; AI325044
NCBI Protein Information
endothelial protein C receptor
UniProt Protein Name
Endothelial protein C receptor
UniProt Gene Name
Procr
UniProt Synonym Gene Names
Epcr; APC receptor
Uniprot Description
EPCR: a single-pass type I membrane protein. Binds activated protein C (APC), a serine protease that regulates thrombin (IIa) production. Plays a pivotal role in preventing blood coagulation through binding of activated protein C. Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. The binding of APC to EPCR and PAR-1 increases invasion and chemotaxis.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 2|2 H1
Cellular Component: cell surface; centrosome; focal adhesion
Molecular Function: protein C-terminus binding
Biological Process: negative regulation of coagulation
Research Articles on sEPCR
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Product Notes
The Mouse sEPCR procr (Catalog #AAA9717264) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717264 ELISA Kit recognizes Mouse sEPCR. It is sometimes possible for the material contained within the vial of "Soluble Endothelial Protein C Receptor (sEPCR), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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