Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Sodium-dependent noradrenaline transporter (SLC6A2) Standard Curve.)
Mouse Sodium-Dependent Noradrenaline Transporter (SLC6A2) ELISA Kit | SLC6A2 elisa kit
Mouse Sodium-Dependent Noradrenaline Transporter (SLC6A2) ELISA Kit
Gene Names
Slc6a2; NET; NE-T; Slc6a5
Reactivity
Mouse
Synonyms
Sodium-Dependent Noradrenaline Transporter (SLC6A2); Mouse Sodium-Dependent Noradrenaline Transporter (SLC6A2) ELISA Kit; SLC6A2; NAT1; NET; NET1; SLC6A5; noradrenaline transporter; norepinephrine transporter; solute carrier family 6 (neurotransmitter transporter; norepinephrine); member 5; solute carrier family 6 member 2; SLC6A2 elisa kit
Reactivity
Mouse
Specificity
Mouse Sodium-dependent noradrenaline transporter (SLC6A2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SLC6A2. No significant cross-reactivity or interference between Mouse SLC6A2 and analogues was observed.
Sequence Length
617
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Sodium-dependent noradrenaline transporter (SLC6A2) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Sodium-dependent noradrenaline transporter (SLC6A2) Standard Curve.)
Related Product Information for SLC6A2 elisa kit
Description: This Mouse Sodium-dependent noradrenaline transporter (SLC6A2) ELISA Kit employs a two-site sandwich ELISA to quantitate SLC6A2 in samples. An antibody specific for SLC6A2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SLC6A2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SLC6A2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SLC6A2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: The norepinephrine transporter or NET is a monoamine transporter that transports the neurotransmitter norepinephrine (noradrenaline) from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. "The norepinephrine transporter (NET) protein consists of 617 amino acids and has 12 transmembrane domains" and is encoded by the SLC6A2 gene. Certain antidepressant medications act to raise noradrenaline, such as the SNRIs and the tricyclic antidepressants (TCAs). In other words, these medications prevent the noradrenaline transporter from doing its job. Noradrenaline therefore remains in the synapse longer, allowing it to reach more normal levels.
Background: The norepinephrine transporter or NET is a monoamine transporter that transports the neurotransmitter norepinephrine (noradrenaline) from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. "The norepinephrine transporter (NET) protein consists of 617 amino acids and has 12 transmembrane domains" and is encoded by the SLC6A2 gene. Certain antidepressant medications act to raise noradrenaline, such as the SNRIs and the tricyclic antidepressants (TCAs). In other words, these medications prevent the noradrenaline transporter from doing its job. Noradrenaline therefore remains in the synapse longer, allowing it to reach more normal levels.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
sodium-dependent noradrenaline transporter
NCBI Official Synonym Full Names
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
NCBI Official Symbol
Slc6a2
NCBI Official Synonym Symbols
NET; NE-T; Slc6a5
NCBI Protein Information
sodium-dependent noradrenaline transporter
UniProt Protein Name
Sodium-dependent noradrenaline transporter
Protein Family
UniProt Gene Name
Slc6a2
UniProt Synonym Gene Names
NET
Uniprot Description
Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.
Research Articles on SLC6A2
Similar Products
Product Notes
The Mouse SLC6A2 slc6a2 (Catalog #AAA9717029) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717029 ELISA Kit recognizes Mouse SLC6A2. It is sometimes possible for the material contained within the vial of "Sodium-Dependent Noradrenaline Transporter (SLC6A2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
