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Mouse Prostaglandin reductase 1, PTGR1 ELISA Kit | PTGR1 elisa kit

Mouse Prostaglandin reductase 1, PTGR1 ELISA Kit

Gene Names
PTGR1; PGR1; ZADH3; LTB4DH
Reactivity
Mouse
Synonyms
Prostaglandin reductase 1; PTGR1; Mouse Prostaglandin reductase 1; PTGR1 ELISA Kit; PTGR1 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Preparation and Storage
Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,870 Da
NCBI Official Full Name
prostaglandin reductase 1 isoform 1
NCBI Official Synonym Full Names
prostaglandin reductase 1
NCBI Official Symbol
PTGR1
NCBI Official Synonym Symbols
PGR1; ZADH3; LTB4DH
NCBI Protein Information
prostaglandin reductase 1; PRG-1; 15-oxoprostaglandin 13-reductase; leukotriene B4 12-hydroxydehydrogenase; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; zinc binding alcohol dehydrogenase domain containing 3
UniProt Protein Name
Prostaglandin reductase 1
Protein Family
UniProt Gene Name
PTGR1
UniProt Synonym Gene Names
LTB4DH; PRG-1
UniProt Entry Name
PTGR1_HUMAN

NCBI Description

This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

Uniprot Description

LTB4DH: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha. Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. Belongs to the NADP-dependent oxidoreductase L4BD family.

Protein type: EC 1.3.1.48; Oxidoreductase; EC 1.3.1.74

Chromosomal Location of Human Ortholog: 9q31.3

Cellular Component: cytoplasm

Molecular Function: 15-oxoprostaglandin 13-oxidase activity; zinc ion binding; 2-alkenal reductase activity

Biological Process: response to toxin; cyclooxygenase pathway; arachidonic acid metabolic process; leukotriene metabolic process

Research Articles on PTGR1

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Product Notes

The Mouse PTGR1 ptgr1 (Catalog #AAA9305527) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9305527 ELISA Kit recognizes Mouse PTGR1. It is sometimes possible for the material contained within the vial of "Prostaglandin reductase 1, PTGR1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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