Mouse Probable ATP-dependent RNA helicase DDX17 (DDX17) ELISA Kit | DDX17 elisa kit

Mouse Probable ATP-dependent RNA helicase DDX17 (DDX17) ELISA Kit

Cat. Num. AAA7233105

• Gene Names: DDX17; P72; RH70
• Reactivity: Mouse
• Synonyms: Probable ATP-dependent RNA helicase DDX17 (DDX17); Mouse Probable ATP-dependent RNA helicase DDX17 (DDX17) ELISA Kit; DDX17 elisa kit

• Reactivity: Mouse

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Assay Type: Competitive
• Detection Range: 0.5-10ng/mL
• Sensitivity: 0.1ng/mL
• Preparation and Storage: Store all reagents at 2-8 degree C.

Product Categories/Family for DDX17 elisa kit

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 148613856
• NCBI GeneID: 10521
• NCBI Accession #: NP_001091974.1
• NCBI GenBank Nucleotide #: NM_001098504.1
• Molecular Weight: 72,557 Da
• NCBI Official Full Name: probable ATP-dependent RNA helicase DDX17 isoform 3
• NCBI Official Synonym Full Names: DEAD (Asp-Glu-Ala-Asp) box helicase 17
• NCBI Official Symbol: DDX17
• NCBI Official Synonym Symbols: P72; RH70
• NCBI Protein Information: probable ATP-dependent RNA helicase DDX17; DEAD box protein p72; RNA-dependent helicase p72; DEAD (Asp-Glu-Ala-Asp) box polypeptide 17; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD)
• UniProt Protein Name: Probable ATP-dependent RNA helicase DDX17
• Protein Family: Probable ATP-dependent RNA helicase
• UniProt Gene Name: DDX17
• UniProt Entry Name: DDX17_HUMAN

NCBI Description

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011]

Uniprot Description

DDX17: RNA-dependent ATPase activity. Involved in transcriptional regulation. Transcriptional coactivator for estrogen receptor ESR1. Increases ESR1 AF-1 domain-mediated transactivation. Synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and probably involved in skeletal muscle differentiation. Required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation. Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA processing; EC 3.6.4.13; Nuclear receptor co-regulator; Transcription, coactivator/corepressor; Spliceosome; Nucleolus; RNA-binding; Helicase

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: nucleoplasm; membrane; nucleolus; nucleus

Molecular Function: protein binding; RNA-dependent ATPase activity; RNA binding; transcription coactivator activity; estrogen receptor binding; ATP binding; RNA helicase activity

Biological Process: RNA processing; transcription, DNA-dependent; positive regulation of estrogen receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter