Mouse Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) ELISA Kit | TIMM8B elisa kit
Mouse Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma.[provided by RefSeq, Aug 2009]
Uniprot Description
TIMM8B: Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. Belongs to the small Tim family.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 11q23.1-q23.2
Cellular Component: mitochondrial intermembrane space protein transporter complex; extracellular space; mitochondrial inner membrane
Molecular Function: zinc ion binding
Biological Process: sensory perception of sound; cellular protein metabolic process; protein targeting to mitochondrion
Research Articles on TIMM8B
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Product Notes
The Mouse TIMM8B timm8b (Catalog #AAA7239039) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7239039 ELISA Kit recognizes Mouse TIMM8B. It is sometimes possible for the material contained within the vial of "Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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