Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Matrix metallopeptidase 7 (MMP7) Standard Curve.)
Mouse Matrix Metallopeptidase 7 (MMP7) ELISA Kit | MMP7 elisa kit
Mouse Matrix Metallopeptidase 7 (MMP7) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Matrix metallopeptidase 7 (MMP7) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Matrix metallopeptidase 7 (MMP7) Standard Curve.)
Background: MMP7, also known as Matrilysin, is the smallest member of the MMP-family, it is a zinc-dependent metalloproteinase and is overexpressed in colon cancer and many other human cancers. MMP7 is a secreted matrix metalloproteinase, which contributes to angiogenesis by breaking down basement membranes. Matrix Metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components.MMP7 is responsible for hydrolyzing proteoglycans and ECM glycoproteins. It is expressed in normal cells, specifically glandular epithelial cells. MMP7, is thought to play an important role in the early steps of tumor progression. Expression of MMP2, MMP7 and MMP11 is greater in pancreatic carcinoma than in normal pancreas.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein are deficient in functional cryptdins. This gene is located in a cluster of other matrix metalloproteinase genes on chromosome 9. [provided by RefSeq, Feb 2016]
Uniprot Description
MMP7: Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. Belongs to the peptidase M10A family.
Protein type: Secreted; EC 3.4.24.23; Secreted, signal peptide; Protease
Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; cell surface; extracellular region
Molecular Function: heparin binding; peptidase activity; metallopeptidase activity; zinc ion binding; hydrolase activity; metal ion binding; metalloendopeptidase activity
Biological Process: response to drug; collagen catabolic process; defense response to Gram-positive bacterium; defense response to bacterium; antibacterial peptide biosynthetic process; proteolysis; defense response to Gram-negative bacterium; antibacterial peptide secretion; regulation of cell proliferation
Research Articles on MMP7
Similar Products
Product Notes
The Mouse MMP7 mmp7 (Catalog #AAA9718160) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9718160 ELISA Kit recognizes Mouse MMP7. It is sometimes possible for the material contained within the vial of "Matrix Metallopeptidase 7 (MMP7), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
