Immunohistochemistry (IHC)
(Anti-MMP7 Picoband antibody, MBS176981-1.JPGIHC(P): Mouse Kidney Tissue )
Rabbit anti-Mouse, Rat MMP7 Polyclonal Antibody | anti-MMP7 antibody
Anti-MMP7 Antibody
Gene Names
Mmp7; MAT
Reactivity
Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Immunogen affinity purified.
Synonyms
MMP7; Polyclonal Antibody; Anti-MMP7 Antibody; Matrilysin; matrix metallopeptidase 7 (matrilysin; uterine); Matrilysin antibody; Matrilysin uterine antibody; Matrin antibody; Matrix Metalloproteinase 7 antibody; Matrix metalloproteinase-7 antibody; MMP 7 antibody; MMP-7 antibody; MMP7 antibody; MMP7_HUMAN antibody; MPSL1 antibody; PUMP 1 antibody; Pump 1 protease antibody; Pump-1 protease antibody; PUMP1 antibody; Uterine Matrilysin antibody; Uterine metalloproteinase antibody; anti-MMP7 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
264
Applicable Applications for anti-MMP7 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Immunogen
E Coli-derived mouse MMP7 recombinant protein (Position: Y95-L264). Mouse MMP7 shares 71% and 90% amino acid (aa) sequences identity with human and rat MMP7, respectively.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Immunohistochemistry (IHC)
(Anti-MMP7 Picoband antibody, MBS176981-1.JPGIHC(P): Mouse Kidney Tissue )
Immunohistochemistry (IHC)
(Anti-MMP7 Picoband antibody, MBS176981-1.JPGIHC(P): Mouse Kidney Tissue )
Immunohistochemistry (IHC)
(Anti-MMP7 Picoband antibody, MBS176981-2.JPGIHC(P): Rat intestines Tissue )
Immunohistochemistry (IHC)
(Anti-MMP7 Picoband antibody, MBS176981-2.JPGIHC(P): Rat intestines Tissue )
Western Blot (WB)
(Anti-MMP7 Picoband antibody, MBS176981-3.jpgAll lanes: Anti-MMP7(MBS176981) at 0.5ug/mlWB: Rat Brain Tissue Lysate at 40ugPredicted bind size: 30KDObserved bind size: 30KD )
Western Blot (WB)
(Anti-MMP7 Picoband antibody, MBS176981-3.jpgAll lanes: Anti-MMP7(MBS176981) at 0.5ug/mlWB: Rat Brain Tissue Lysate at 40ugPredicted bind size: 30KDObserved bind size: 30KD )
Related Product Information for anti-MMP7 antibody
Description: Rabbit IgG polyclonal antibody for Matrilysin(MMP7) detection. Tested with WB, IHC-P, ELISA in Mouse, Rat.
Background: Matrix metalloproteinase-7 (MMP-7) previously called putative metalloproteinase I (PUMP1) or matrilysin. The MMP-7 gene has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors. The MMP-7 protein has 267 amino acids and is significantly shorter than stromelysin or collagenase (477 and 469 amino acids, respectively). Matrix metalloproteinases play a crucial role in tumor invasion and metastasis. MMP-7, a member of the matrix metalloproteinase family, is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain. In addition, MMP-7 mRNA is regulated in a specific and distinct manner in normal and malignant tissues. MMP-7 has been shown to correlate with nodal or distant metastasis in colorectal carcinomas, however, its implication in early invasive colorectal carcinomas has not been determined. MMP-7 is also a mediator of pulmonary fibrosis and a potential therapeutic target. The standard product used in this kit is recombinant human MMP-7, consisting of 250 amino acids with the molecular mass of 28KDa. The detected MMP-7 includes zymogen and active enzyme.
Background: Matrix metalloproteinase-7 (MMP-7) previously called putative metalloproteinase I (PUMP1) or matrilysin. The MMP-7 gene has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors. The MMP-7 protein has 267 amino acids and is significantly shorter than stromelysin or collagenase (477 and 469 amino acids, respectively). Matrix metalloproteinases play a crucial role in tumor invasion and metastasis. MMP-7, a member of the matrix metalloproteinase family, is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain. In addition, MMP-7 mRNA is regulated in a specific and distinct manner in normal and malignant tissues. MMP-7 has been shown to correlate with nodal or distant metastasis in colorectal carcinomas, however, its implication in early invasive colorectal carcinomas has not been determined. MMP-7 is also a mediator of pulmonary fibrosis and a potential therapeutic target. The standard product used in this kit is recombinant human MMP-7, consisting of 250 amino acids with the molecular mass of 28KDa. The detected MMP-7 includes zymogen and active enzyme.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
29,755 Da
NCBI Official Full Name
Matrilysin
NCBI Official Synonym Full Names
matrix metallopeptidase 7
NCBI Official Symbol
Mmp7
NCBI Official Synonym Symbols
MAT
NCBI Protein Information
matrilysin; MMP-7; matrin; pump-1 protease; matrilysin, uterine; uterine metalloproteinase; matrix metalloproteinase 7; matrix metalloproteinase-7
UniProt Protein Name
Matrilysin
Protein Family
UniProt Gene Name
Mmp7
UniProt Synonym Gene Names
MMP-7
UniProt Entry Name
MMP7_MOUSE
Uniprot Description
MMP7: Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. Belongs to the peptidase M10A family.
Protein type: Protease; Secreted; EC 3.4.24.23; Secreted, signal peptide
Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; cell surface; extracellular region
Molecular Function: heparin binding; peptidase activity; hydrolase activity; metallopeptidase activity; zinc ion binding; metal ion binding; metalloendopeptidase activity
Biological Process: response to drug; collagen catabolic process; defense response to Gram-positive bacterium; defense response to bacterium; antibacterial peptide biosynthetic process; defense response to Gram-negative bacterium; proteolysis; antibacterial peptide secretion; regulation of cell proliferation
Research Articles on MMP7
Similar Products
Product Notes
The MMP7 mmp7 (Catalog #AAA176981) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MMP7 Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MMP7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA). Researchers should empirically determine the suitability of the MMP7 mmp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMP7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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