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Testing Data (The OmniKine Murine IL-12 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Murine IL-12 proteins within the range of 16-1000 pg/ml.)

Mouse IL-12 ELISA Kit | IL-12 elisa kit

IL-12 (Murine) OmniKine ELISA Kit

Gene Names
Il12a; p35; Ll12a; Il-12a; IL-12p35
Reactivity
Mouse
Synonyms
IL-12; IL-12 (Murine) OmniKine ELISA Kit; Interleukin-12; Cytotoxic lymphocyte maturation factor; IL-12 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Specificity
The OmniKine Murine IL-12 ELISA is capable of recognizing both recombinant and naturally produced Murine IL-12 proteins. The antigens listed below were tested at 50 ng/ml and exhibited 100% cross reactivity.
Murine: IL-12p40, IL-12p80
The antigens listed below were tested at 50 ng/ml and exhibited less than 1% cross reactivity.
Human: IL-12p40, IL-12p70, IL-12p80
The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: IFN-gamma, IL-10
Murine: IFN-gamma, IL-10
Form/Format
12 x 8-Well Microstrips
Sequence Length
236
Samples
Plasma, serum, lysate
Assay Type
Sandwich ELISA
Detection Range
16-1000 pg/ml
Sensitivity
16-1000 pg/ml
Detection Method
Colorimetric 450 nm
Subtype
None
Preparation and Storage
Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Murine IL-12 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Murine IL-12 proteins within the range of 16-1000 pg/ml.)

Testing Data (The OmniKine Murine IL-12 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Murine IL-12 proteins within the range of 16-1000 pg/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,179 Da
NCBI Official Full Name
interleukin-12 subunit alpha isoform 1
NCBI Official Synonym Full Names
interleukin 12a
NCBI Official Symbol
Il12a
NCBI Official Synonym Symbols
p35; Ll12a; Il-12a; IL-12p35
NCBI Protein Information
interleukin-12 subunit alpha
UniProt Protein Name
Interleukin-12 subunit alpha
UniProt Gene Name
Il12a
UniProt Synonym Gene Names
IL-12A; CLMF p35

Uniprot Description

IL12A: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-6 superfamily.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3 E1|3 31.92 cM

Cellular Component: cytoplasm; extracellular region; extracellular space; interleukin-12 complex

Molecular Function: cytokine activity; growth factor activity; interleukin-12 beta subunit binding; interleukin-12 receptor binding; interleukin-27 binding; protein heterodimerization activity

Biological Process: cell cycle arrest; cell migration; cell proliferation; defense response to protozoan; immune response; interferon-gamma production; negative regulation of interleukin-17 production; negative regulation of smooth muscle cell proliferation; positive regulation of cell adhesion; positive regulation of interferon-gamma production; positive regulation of lymphocyte proliferation; positive regulation of mononuclear cell proliferation; positive regulation of natural killer cell activation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; positive regulation of NK T cell activation; positive regulation of T cell differentiation; positive regulation of T cell mediated cytotoxicity; positive regulation of T cell proliferation; positive regulation of tyrosine phosphorylation of STAT protein; response to lipopolysaccharide; response to UV-B

Research Articles on IL-12

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Product Notes

The Mouse IL-12 il12a (Catalog #AAA9501905) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9501905 ELISA Kit recognizes Mouse IL-12. It is sometimes possible for the material contained within the vial of "IL-12, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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