Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Histone acetyltransferase MYST2 (MYST2) Standard Curve.)
Mouse Histone Acetyltransferase MYST2 (MYST2) ELISA Kit | MYST2 elisa kit
Mouse Histone Acetyltransferase MYST2 (MYST2) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Histone acetyltransferase MYST2 (MYST2) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Histone acetyltransferase MYST2 (MYST2) Standard Curve.)
Background: The K(lysine) acetyltransferase 7 encoded by Kat7 is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed.
NCBI and Uniprot Product Information
Uniprot Description
MYST2: a histone acetyltransferase that participates in DNA replication and the loading of the minichromosome maintenance (Mcm) complex onto chromatin. Is required for origin recognition complex (Orc) formation and replication licensing, and is responsible for much of the acetylation of histone H4. Interacts with MCM2 and ORC1L. Phosphorylated by Cdc2 during mitosis, creating a site that recruits Plk1, which in turn phosphorylates MYST2. Its phosphorylation by Plk1 during mitosis may be required for the formation of the prereplicative complex. Interacts with the androgen receptor (AR) in the presence of dihydrotestosterone. Specifically represses AR-mediated transcription.
Protein type: Acetyltransferase; Nuclear receptor co-regulator; Transcription, coactivator/corepressor; EC 2.3.1.48
Cellular Component: nucleoplasm; cytoplasm; nucleus; histone acetyltransferase complex
Molecular Function: transferase activity; histone acetyltransferase activity; zinc ion binding; metal ion binding; transferase activity, transferring acyl groups; transferase activity, transferring groups other than amino-acyl groups; transcription factor activity
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; chromatin modification; DNA replication
Research Articles on MYST2
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Product Notes
The Mouse MYST2 kat7 (Catalog #AAA9717461) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717461 ELISA Kit recognizes Mouse MYST2. It is sometimes possible for the material contained within the vial of "Histone Acetyltransferase MYST2 (MYST2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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