Mouse Fibronectin Type III Domain Containing Protein 5 (FNDC5) ELISA Kit | FNDC5 elisa kit

Mouse Fibronectin Type III Domain Containing Protein 5 (FNDC5) ELISA Kit

Cat. Num. AAA456458

• Gene Names: Fndc5; PeP; Pxp; C87088; AI836596; 1500001L03Rik
• Reactivity: Mouse
• Synonyms: Fibronectin Type III Domain Containing Protein 5 (FNDC5); Mouse Fibronectin Type III Domain Containing Protein 5 (FNDC5) ELISA Kit; FRCP2 Irisin •Fibronectin type III repeat-containing protein 2; FNDC5 elisa kit

• Reactivity: Mouse
• Sequence Length: 209

• Samples: Serum, plasma and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.625-40ng/mL
• Sensitivity: 0.246ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 47059145
• NCBI GeneID: 384061
• NCBI Accession #: NP_081678.1
• NCBI GenBank Nucleotide #: NM_027402.4
• UniProt Accession #: Q8K4Z2; Q9DB97
• Molecular Weight: 23,321 Da
• NCBI Official Full Name: fibronectin type III domain-containing protein 5 preproprotein
• NCBI Official Synonym Full Names: fibronectin type III domain containing 5
• NCBI Official Symbol: Fndc5
• NCBI Official Synonym Symbols: PeP; Pxp; C87088; AI836596; 1500001L03Rik
• NCBI Protein Information: fibronectin type III domain-containing protein 5
• UniProt Protein Name: Fibronectin type III domain-containing protein 5
• Protein Family: Fibronectin type III domain-containing protein
• UniProt Gene Name: Fndc5
• UniProt Synonym Gene Names: Frcp2; Pep; PeP

NCBI Description

This gene encodes a type I transmembrane protein containing fibronectin type III repeat. The encoded transmembrane protein undergoes proteolytic processing to generate a soluble hormone named irisin that is secreted into the bloodstream. The expression of this gene followed by the secretion of irisin from skeletal muscle is induced by exercise. The ectopic expression of the encoded protein in mice causes an elevation of irisin in blood and improves metabolic health. [provided by RefSeq, Jul 2016]

Uniprot Description

Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.