Western Blot (WB)
(Western Blot (WB) analysis of DPP7 polyclonal antibody at 1:500 dilutionLane1:MCF-7 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:U-87MG whole cell lysate (40ug))
Rabbit anti-Human DPP7 Polyclonal Antibody | anti-DPP7 antibody
DPP7 Polyclonal Antibody
Gene Names
DPP7; QPP; DPP2; DPPII
Reactivity
Human
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
DPP7; Polyclonal Antibody; DPP7 Polyclonal Antibody; Dipeptidyl peptidase 2; Dipeptidyl aminopeptidase II; Dipeptidyl peptidase 7; Dipeptidyl peptidase II; DPP II; Quiescent cell proline dipeptidase; DPP2; QPP; anti-DPP7 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
DPP7 polyclonal antibody detects endogenous levels of DPP7 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
492
Applicable Applications for anti-DPP7 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding to amino acids 430-480 of Human DPP7.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of DPP7 polyclonal antibody at 1:500 dilutionLane1:MCF-7 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:U-87MG whole cell lysate (40ug))
Western Blot (WB)
(Western Blot (WB) analysis of DPP7 polyclonal antibody at 1:500 dilutionLane1:MCF-7 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:U-87MG whole cell lysate (40ug))
Related Product Information for anti-DPP7 antibody
Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPP7 (dipeptidyl-peptidase 7), also known as DPP2, DPPII or QPP (quiescent cell proline dipeptidase), is expressed in quiescent lymphocytes and localizes to lysosomes. In response to calcium release, DPP7 can be secreted in its active form. DPP7 exists as a homodimer via its leucine zipper motif and is involved in the degradation of oligopeptides. DPP7 is essential for lymphocyte survival, as the inhibition of DPP7 results in quiescent cell apoptosis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 54kDa
NCBI Official Full Name
dipeptidyl peptidase 2 preproprotein
NCBI Official Synonym Full Names
dipeptidyl peptidase 7
NCBI Official Symbol
DPP7
NCBI Official Synonym Symbols
QPP; DPP2; DPPII
NCBI Protein Information
dipeptidyl peptidase 2
UniProt Protein Name
Dipeptidyl peptidase 2
Protein Family
UniProt Gene Name
DPP7
UniProt Synonym Gene Names
DPP2; QPP
UniProt Entry Name
DPP2_HUMAN
NCBI Description
The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. [provided by RefSeq, Jul 2008]
Research Articles on DPP7
Similar Products
Product Notes
The DPP7 dpp7 (Catalog #AAA3007652) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DPP7 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DPP7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the DPP7 dpp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DPP7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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