Mouse Dystrophin (DMD) ELISA Kit | DMD elisa kit

Mouse Dystrophin (DMD) ELISA Kit

Cat. Num. AAA453034

• Gene Names: Dmd; dys; mdx; pke; Dp71; Dp427; DXSmh7; DXSmh9
• Reactivity: Mouse
• Synonyms: Dystrophin (DMD); Mouse Dystrophin (DMD) ELISA Kit; CMD3B; Muscular Dystrophy; Duchenne And Becker Types; DMD elisa kit

• Reactivity: Mouse
• Sequence Length: 3678

• Samples: Tissue homogenates, cell lysates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.312-20ng/mL
• Sensitivity: 0.108ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 6681203
• NCBI GeneID: 13405
• NCBI Accession #: NP_031894.1
• NCBI GenBank Nucleotide #: NM_007868.6
• UniProt Accession #: P11531; O35653; Q60703; A2A9Z0
• Molecular Weight: 425,832 Da
• NCBI Official Full Name: dystrophin isoform 1
• NCBI Official Synonym Full Names: dystrophin, muscular dystrophy
• NCBI Official Symbol: Dmd
• NCBI Official Synonym Symbols: dys; mdx; pke; Dp71; Dp427; DXSmh7; DXSmh9
• NCBI Protein Information: dystrophin
• UniProt Protein Name: Dystrophin
• Protein Family: Dystrophin
• UniProt Gene Name: Dmd

NCBI Description

This gene encodes a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers in skeletal and cardiac muscles. The encoded protein, dystrophin, is part of the dystrophin-glycoprotein complex, which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix. This protein is required for proper development and organization of myofibers as contractile units in striated muscles. Mutations in the human gene cause Duchenne and Becker Muscular Dystrophies and a form of heart disease called DMD-associated dilated cardiomyopathy. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Sep 2015]

Uniprot Description

Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.