Mouse cAMP-responsive element modulator (CREM) ELISA Kit | CREM elisa kit

Mouse cAMP-responsive element modulator (CREM) ELISA Kit

Gene Names

CREM; ICER; CREM-2; hCREM-2

Reactivity

Mouse

Synonyms

cAMP-responsive element modulator (CREM); Mouse cAMP-responsive element modulator (CREM) ELISA Kit; CREM elisa kit

Ordering
Cat. Num. AAA7214952 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Mouse

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Preparation and Storage

Store all reagents at 2-8 degree C.

Product Categories/Family for CREM elisa kit

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

NCBI GI #

389616137

NCBI GeneID

1390

NCBI Accession #

NP_001254498.1

NCBI GenBank Nucleotide #

NM_001267569.1

Molecular Weight

26,269 Da

NCBI Official Full Name

cAMP-responsive element modulator isoform 30

NCBI Official Synonym Full Names

cAMP responsive element modulator

NCBI Official Symbol

CREM

NCBI Official Synonym Symbols

ICER; CREM-2; hCREM-2

NCBI Protein Information

cAMP-responsive element modulator; CREM 2beta-a protein; CREM 2alpha-b protein; cAMP response element modulator; inducible cAMP early repressor ICER

UniProt Protein Name

cAMP-responsive element modulator

Protein Family

cAMP-responsive element modulator

UniProt Gene Name

CREM

UniProt Synonym Gene Names

ICER

UniProt Entry Name

CREM_HUMAN

NCBI Description

This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]

Uniprot Description

CREM: a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. An important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative splice isoforms allow this protein to exert spatial and temporal specificity to cAMP responsiveness. Twentyeight alternatively spliced isoforms of the human protein have been described, with some of them functioning as activators and some as repressors of transcription.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 10p11.21

Cellular Component: transcription factor complex; cytoplasm; nucleus

Molecular Function: protein binding; DNA binding; cAMP response element binding protein binding; transcription factor activity

Biological Process: response to cAMP; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter; glycosphingolipid metabolic process; circadian regulation of gene expression; signal transduction; cell differentiation; negative regulation of transcription, DNA-dependent

Research Articles on CREM

1. CaMK4-dependent activation of AKT/mTOR and CREM-alpha underlies autoimmunity-associated Th17 imbalance.

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Product Notes

The Mouse CREM crem (Catalog #AAA7214952) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7214952 ELISA Kit recognizes Mouse CREM. It is sometimes possible for the material contained within the vial of "cAMP-responsive element modulator (CREM), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Mouse cAMP-responsive element modulator (CREM) ELISA Kit | CREM elisa kit