Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse C-type mannose receptor 2 (MRC2) Standard Curve.)
Mouse C-Type Mannose Receptor 2 (MRC2) ELISA Kit | MRC2 elisa kit
Mouse C-Type Mannose Receptor 2 (MRC2) ELISA Kit
Gene Names
Mrc2; uPARAP; Endo180; mKIAA0709
Reactivity
Mouse
Synonyms
C-Type Mannose Receptor 2 (MRC2); Mouse C-Type Mannose Receptor 2 (MRC2) ELISA Kit; MRC2; CD280; CLEC13E; ENDO180; FLJ35911; KIAA0709; UPARAP; endocytic receptor (macrophage mannose receptor family); urokinase plasminogen activator receptor-associated protein; MRC2 elisa kit
Reactivity
Mouse
Specificity
Mouse C-type mannose receptor 2 (MRC2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MRC2. No significant cross-reactivity or interference between Mouse MRC2 and analogues was observed.
Sequence Length
1479
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse C-type mannose receptor 2 (MRC2) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse C-type mannose receptor 2 (MRC2) Standard Curve.)
Related Product Information for MRC2 elisa kit
Description: This Mouse C-type mannose receptor 2 (MRC2) ELISA Kit employs a two-site sandwich ELISA to quantitate MRC2 in samples. An antibody specific for MRC2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any MRC2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MRC2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MRC2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: MRC2 encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The mannose receptor C type 2 plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
Background: MRC2 encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The mannose receptor C type 2 plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
C-type mannose receptor 2
NCBI Official Synonym Full Names
mannose receptor, C type 2
NCBI Official Symbol
Mrc2
NCBI Official Synonym Symbols
uPARAP; Endo180; mKIAA0709
NCBI Protein Information
C-type mannose receptor 2
UniProt Protein Name
C-type mannose receptor 2
Protein Family
UniProt Gene Name
Mrc2
UniProt Synonym Gene Names
Kiaa0709
Uniprot Description
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
Research Articles on MRC2
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Product Notes
The Mouse MRC2 mrc2 (Catalog #AAA9717562) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717562 ELISA Kit recognizes Mouse MRC2. It is sometimes possible for the material contained within the vial of "C-Type Mannose Receptor 2 (MRC2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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