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Mouse Activin receptor type-2B, ACVR2B ELISA Kit | ACVR2B elisa kit

Mouse Activin receptor type-2B, ACVR2B ELISA Kit

Reactivity
Mouse
Synonyms
Activin receptor type-2B; ACVR2B; Mouse Activin receptor type-2B; ACVR2B ELISA Kit; ACVR2B elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Sequence Length
512
Assay Type
Quantitative Sandwich
Samples
Serum, plasma, cell culture supernates, cell lysates, tissue homogenates and other biological fluids.
Detection Range
10 ng/L-2000 ng/L
Sensitivity
5.48 ng/L
Preparation and Storage
Store at 2 to 8 degree C for 6 months.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
activin receptor type-2B
NCBI Official Synonym Full Names
activin A receptor type 2B
NCBI Official Symbol
Acvr2b
NCBI Protein Information
activin receptor type-2B
UniProt Protein Name
Activin receptor type-2B
Protein Family
UniProt Gene Name
Acvr2b
UniProt Synonym Gene Names
Actriib; ACTR-IIB

NCBI Description

plays a role in reproductive physiology and endocrinology [RGD, Feb 2006]

Uniprot Description

ACVR2B: a tyrosine-kinase like receptor kinase of the STKR family. The holoreceptor receptor is a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. Each is composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic kinase domain. Type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptor kinases are apparently constitutively active. The IIB receptor displays a 3- to 4-fold higher affinity for activin A than the II receptor.

Protein type: EC 2.7.11.30; Kinase, protein; Membrane protein, integral; Protein kinase, Ser/Thr (receptor); Protein kinase, TKL; STKR family; TKL group; Type2 subfamily

Chromosomal Location of Human Ortholog: 8q32

Cellular Component: cytoplasm; integral component of membrane; plasma membrane; protein complex; receptor complex

Molecular Function: activin binding; ATP binding; growth factor binding; metal ion binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; signal transducer, downstream of receptor, with serine/threonine kinase activity; transforming growth factor beta binding; transmembrane receptor protein serine/threonine kinase activity

Biological Process: activation of protein kinase activity; activin receptor signaling pathway; anterior/posterior pattern specification; blood vessel remodeling; BMP signaling pathway; determination of left/right symmetry; embryonic foregut morphogenesis; gastrulation with mouth forming second; heart development; insulin secretion; kidney development; lung development; lymphangiogenesis; mesoderm development; negative regulation of transcription from RNA polymerase II promoter; odontogenesis of dentine-containing teeth; organ growth; palate development; pancreas development; pattern specification process; positive regulation of activin receptor signaling pathway; positive regulation of bone mineralization; positive regulation of osteoblast differentiation; post-embryonic development; protein amino acid phosphorylation; regulation of signal transduction; regulation of transcription, DNA-templated; response to glucose stimulus; sexual reproduction; signal transduction; skeletal morphogenesis; skeletal system development; transmembrane receptor protein serine/threonine kinase signaling pathway

Research Articles on ACVR2B

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Product Notes

The Mouse ACVR2B acvr2b (Catalog #AAA1604544) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA1604544 ELISA Kit recognizes Mouse ACVR2B. It is sometimes possible for the material contained within the vial of "Activin receptor type-2B, ACVR2B, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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