Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse 43 kDa receptor-associated protein of the synapse (RAPSN) Standard Curve.)
Mouse 43 kDa Receptor-Associated Protein Of The synapse (RAPSN) ELISA Kit | RAPSN elisa kit
Mouse 43 kDa Receptor-Associated Protein Of The synapse (RAPSN) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse 43 kDa receptor-associated protein of the synapse (RAPSN) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse 43 kDa receptor-associated protein of the synapse (RAPSN) Standard Curve.)
Background: 43 kDa receptor-associated protein of the synapse is a protein belongs to a family of proteins that are receptor associated proteins of the synapse. It contains a conserved cAMP-dependent protein kinase phosphorylation site. It is believed to play some role in anchoring or stabilizing the nicotinic acetylcholine receptor at synaptic sites. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Two splice variants have been identified for this gene. Thought to play some role in anchoring or stabilizing the nicotinic acetylcholine receptor at synaptic sites. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin.
NCBI and Uniprot Product Information
Uniprot Description
RAPSN: Thought to play some role in anchoring or stabilizing the nicotinic acetylcholine receptor at synaptic sites. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Defects in RAPSN are a cause of congenital myasthenic syndrome with acetylcholine receptor deficiency (CMS-ACHRD). A postsynaptic congenital myasthenic syndrome. Congenital myasthenic syndromes (CMS) are inherited disorders of neuromuscular transmission that stem from mutations in presynaptic, synaptic, or postsynaptic proteins. Defects in RAPSN are the cause of fetal akinesia deformation sequence (FADS); also known as Pena- Shokeir syndrome type 1 or fetal akinesia sequence or arthrogryposis multiplex congenita with pulmonary hypoplasia. FADS is a rare condition characterized by decreased intrauterine fetal movement, congenital limb contractures, pulmonary hypoplasia, polyhydramnios and craniofacial abnormalities. Belongs to the RAPsyn family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Cell adhesion; Ubiquitin conjugating system
Cellular Component: Golgi apparatus; postsynaptic membrane; centrosome; cytoskeleton; membrane; cytoplasm; plasma membrane; synapse; neuromuscular junction; cell junction
Molecular Function: ionotropic glutamate receptor binding; zinc ion binding; protein anchor; metal ion binding; acetylcholine receptor binding
Biological Process: synaptic transmission; positive regulation of neuron apoptosis; synaptic transmission, cholinergic
Research Articles on RAPSN
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Product Notes
The Mouse RAPSN rapsn (Catalog #AAA9717184) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717184 ELISA Kit recognizes Mouse RAPSN. It is sometimes possible for the material contained within the vial of "43 kDa Receptor-Associated Protein Of The synapse (RAPSN), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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